Detailed information NTG0761407

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: OS912_RS04885
• Genome accession: NZ_CP113266
• Coordinates: 968400..969437 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727273.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain BC1
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 963400..974437

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OS912_RS04860 (OS912_04865)	-	964139..965470 (-)	1332	WP_000390039.1	hemolysin family protein	-
OS912_RS04865 (OS912_04870)	endA	965761..966585 (-)	825	WP_001036784.1	DNA-entry nuclease EndA	Machinery gene
OS912_RS04870 (OS912_04875)	-	966624..966812 (-)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
OS912_RS04875 (OS912_04880)	murA	966805..968088 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
OS912_RS04880 (OS912_04885)	-	968112..968342 (-)	231	WP_000250392.1	DUF1146 family protein	-
OS912_RS04885 (OS912_04890)	sepM	968400..969437 (-)	1038	WP_000727273.1	SepM family pheromone-processing serine protease	Regulator
OS912_RS04890 (OS912_04895)	coaD	969421..969909 (-)	489	WP_001280751.1	pantetheine-phosphate adenylyltransferase	-
OS912_RS04895 (OS912_04900)	rsmD	969899..970438 (-)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
OS912_RS04900 (OS912_04905)	asnA	970503..971495 (-)	993	WP_061816329.1	aspartate--ammonia ligase	-
OS912_RS04905 (OS912_04910)	-	971607..972290 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
OS912_RS04910 (OS912_04915)	-	972346..973086 (-)	741	WP_000152678.1	TrmH family RNA methyltransferase	-
OS912_RS04915 (OS912_04920)	-	973120..973398 (+)	279	WP_001174613.1	acylphosphatase	-
OS912_RS04920 (OS912_04925)	yidC	973476..974402 (+)	927	WP_000835955.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37519.54 Da
• Isoelectric Point: 5.0724

>NTDB_id=761407 OS912_RS04885 WP_000727273.1 968400..969437(-) (sepM) [Streptococcus pneumoniae strain BC1]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFLRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=761407 OS912_RS04885 WP_000727273.1 968400..969437(-) (sepM) [Streptococcus pneumoniae strain BC1]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTCTGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588