Detailed information NTG0761269

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: ORP33_RS12745
• Genome accession: NZ_CP113256
• Coordinates: 2483347..2485677 (-)
• Length: 776 a.a.
• NCBI ID: WP_213414606.1
• Uniprot ID: -
• Organism: Bacillus subtilis strain K1
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2478347..2490677

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ORP33_RS12710 (ORP33_12470)	yqxA	2478686..2479024 (-)	339	WP_087614625.1	YqxA family protein	-
ORP33_RS12715 (ORP33_12475)	spoIIP	2479041..2480246 (-)	1206	WP_003229993.1	spore autolysin SpoIIP	-
ORP33_RS12720 (ORP33_12480)	gpr	2480309..2481415 (-)	1107	WP_003229991.1	GPR endopeptidase	-
ORP33_RS12725 (ORP33_12485)	rpsT	2481619..2481885 (+)	267	WP_131227637.1	30S ribosomal protein S20	-
ORP33_RS12730 (ORP33_12490)	holA	2481900..2482943 (-)	1044	WP_014480310.1	DNA polymerase III subunit delta	-
ORP33_RS12735	-	2482983..2483132 (-)	150	WP_003229985.1	hypothetical protein	-
ORP33_RS12740 (ORP33_12495)	yqzM	2483173..2483307 (+)	135	WP_003229983.1	YqzM family protein	-
ORP33_RS12745 (ORP33_12500)	comEC	2483347..2485677 (-)	2331	WP_213414606.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ORP33_RS12750 (ORP33_12505)	comEB	2485681..2486250 (-)	570	WP_003229978.1	ComE operon protein 2	-
ORP33_RS12755 (ORP33_12510)	comEA	2486317..2486934 (-)	618	WP_122894878.1	competence protein ComEA	Machinery gene
ORP33_RS12760 (ORP33_12515)	comER	2487018..2487839 (+)	822	WP_213414605.1	late competence protein ComER	-
ORP33_RS12765 (ORP33_12520)	yqeM	2487905..2488648 (-)	744	WP_015384134.1	class I SAM-dependent DNA methyltransferase	-
ORP33_RS12770 (ORP33_12525)	rsfS	2488645..2489001 (-)	357	WP_014477391.1	ribosome silencing factor	-
ORP33_RS12775 (ORP33_12530)	yqeK	2489019..2489579 (-)	561	WP_014480316.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
ORP33_RS12780 (ORP33_12535)	nadD	2489569..2490138 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
ORP33_RS12785 (ORP33_12540)	yhbY	2490150..2490440 (-)	291	WP_213414604.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86628.11 Da
• Isoelectric Point: 7.0494

>NTDB_id=761269 ORP33_RS12745 WP_213414606.1 2483347..2485677(-) (comEC) [Bacillus subtilis strain K1]
MRNSRLLLPMAAASATVGITAAAYFPAIFLFILFLLIILIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIDTIPKIDGDRMSMMVETPDKEKWAAAYRIQSAGEKEQLLYIEPGMSCELTGTLEEPNHATVPGAFDYNEYLYRQHI
HWNYSVTSIQNCSEPENFKYKVLSLRKHIISFTNSLLPPDSAGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHV
GILTAGLFYIMIRLGITREKASILLLLFLPLYVMLTGAAPSVLRAALMSGVYLAGSLVKWRVHSATAICLSYIVLLLFNP
YHLFEAGFQLSFAVSFSLILSSSIFQQVKTSLGQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFYTFCILPGA
VAGVLLLSLSASFGRLFFSWFDLLISWTNRLITNIADVDVFTIMIAHPAPVLLFLFTVTIILLLMAIEKRSLSQLMVTGG
ICCTVLFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFSLGEKVLIPFLTAKG
IKQLDALILTHADQDHIGEAETLLKHHKVKRLVIPKGFVSEPKDEKVLQTAREEGVTIEEVKRGDVLQIKDLQFHVLSPG
APDPASKNNSSLVLWMETGGMSWILTGDLEKEGEQEVMDVFPNIKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGKN
NRYHHPHQEVLQLLQRHSIRVLRTDQNGTIQYRYKNRVGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=761269 ORP33_RS12745 WP_213414606.1 2483347..2485677(-) (comEC) [Bacillus subtilis strain K1]
ATGCGTAATTCGCGTTTGTTATTGCCTATGGCGGCAGCTTCGGCAACGGTTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATTTTAATCAAAACGAGGCACGCTTTTCTCATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACCTATCAATTC
AAGGCAGTGATTGACACTATTCCCAAAATTGACGGCGACCGTATGTCTATGATGGTTGAGACACCTGATAAGGAAAAATG
GGCTGCTGCGTATCGCATTCAGTCTGCTGGTGAAAAAGAACAGCTGTTATACATAGAACCAGGAATGTCATGTGAGTTGA
CTGGTACATTGGAAGAACCGAATCACGCAACTGTGCCGGGTGCATTTGATTATAACGAGTATCTTTATCGGCAGCATATT
CATTGGAACTACTCTGTCACGTCTATCCAAAACTGCAGCGAACCTGAAAATTTTAAGTACAAGGTGCTCAGCTTGAGAAA
ACATATCATATCATTCACAAACAGCCTTTTGCCTCCTGATTCAGCAGGGATTGTACAGGCACTTACAGTTGGTGACAGAT
TTTATGTGGAGGATGAAGTGCTTACCGCGTATCAAAAGCTTGGTGTTGTCCATCTCTTGGCAATATCAGGACTCCACGTG
GGGATTTTGACAGCAGGTTTGTTTTATATCATGATTCGCCTTGGTATAACTAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCGCTCTATGTGATGTTGACCGGCGCTGCTCCTTCAGTGCTACGCGCCGCTCTCATGTCGGGTGTTTACTTAG
CTGGAAGCCTTGTCAAATGGCGTGTCCACTCTGCAACTGCAATTTGCCTTTCATACATCGTCCTTCTGCTCTTCAATCCT
TATCATCTCTTTGAAGCCGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCAGCA
GGTTAAAACCTCCTTGGGACAGCTGACAATTGTATCACTCATCGCTCAGCTGGGCTCGCTTCCGATTCTTCTATATCATT
TTCATCAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTCTGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGCTTCGTTTGGGAGATTGTTTTTCAGCTGGTTTGATTTATTGATAAGCTG
GACCAATAGGCTAATCACAAACATTGCAGATGTTGATGTGTTCACGATTATGATCGCACATCCTGCACCTGTTTTGCTTT
TTTTATTCACGGTCACGATCATCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGGTAACCGGAGGC
ATTTGCTGCACGGTGCTGTTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTGGATATGATAGATATTGG
ACAGGGTGACAGCATGTTTGTAGGTGCTCCGCATCAGCGGGGGCGTGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCGCGAAAAACAGCATCCGTTTTCACTGGGGGAAAAGGTGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAACAGCTTGACGCTTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGACTCTGCTGAAGCATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAAGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGACAGCCAGAGAAG
AGGGAGTGACAATTGAAGAGGTGAAGCGAGGAGATGTATTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCTGGA
GCACCTGATCCGGCAAGCAAAAATAATTCCTCTCTCGTTCTGTGGATGGAGACGGGCGGTATGAGCTGGATCTTGACGGG
TGACCTGGAGAAAGAAGGGGAACAGGAGGTGATGGACGTGTTTCCAAATATTAAAGCAGATGTCTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCATCCAACAGCTTCAGCCGAAAACGGCCATTATCTCAGCCGGGAAAAAC
AATCGGTACCATCATCCTCATCAAGAAGTTCTGCAACTATTACAGAGACATTCTATCCGCGTGCTGCGAACAGATCAAAA
CGGAACGATCCAATATAGATACAAAAACAGAGTTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

• Competence protein (Competence) (208-469)

• Domain of unknown function (DUF4131) (DUF4131) (20-170)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	98.582	100	0.986