Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   OTU47_RS06100 Genome accession   NZ_CP113115
Coordinates   1138785..1140017 (+) Length   410 a.a.
NCBI ID   WP_000106346.1    Uniprot ID   A0A064C077
Organism   Streptococcus pneumoniae strain NP2     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1133785..1145017
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTU47_RS06070 (OTU47_06070) - 1133898..1134575 (+) 678 WP_267742120.1 DnaD domain-containing protein -
  OTU47_RS06075 (OTU47_06075) tpiA 1134674..1135432 (+) 759 WP_000087891.1 triose-phosphate isomerase -
  OTU47_RS06080 (OTU47_06080) lytC 1135470..1136960 (+) 1491 WP_267742109.1 choline binding-anchored murein hydrolase LytC -
  OTU47_RS06085 (OTU47_06085) - 1137424..1137942 (+) 519 WP_267742107.1 Dps family protein -
  OTU47_RS06090 (OTU47_06090) - 1138072..1138578 (+) 507 WP_267742105.1 dihydrofolate reductase -
  OTU47_RS06095 (OTU47_06095) - 1138578..1138748 (+) 171 WP_000442258.1 hypothetical protein -
  OTU47_RS06100 (OTU47_06100) clpX 1138785..1140017 (+) 1233 WP_000106346.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  OTU47_RS06105 (OTU47_06105) yihA 1140026..1140613 (+) 588 WP_000422597.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  OTU47_RS06110 (OTU47_06110) - 1140624..1141004 (+) 381 WP_001140412.1 RidA family protein -
  OTU47_RS06115 (OTU47_06115) rapZ 1141056..1141946 (+) 891 WP_000163035.1 RNase adapter RapZ -
  OTU47_RS06120 (OTU47_06120) - 1141943..1142920 (+) 978 WP_001231086.1 YvcK family protein -
  OTU47_RS06125 (OTU47_06125) whiA 1142917..1143828 (+) 912 WP_000011306.1 DNA-binding protein WhiA -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45798.35 Da        Isoelectric Point: 4.4550

>NTDB_id=760440 OTU47_RS06100 WP_000106346.1 1138785..1140017(+) (clpX) [Streptococcus pneumoniae strain NP2]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=760440 OTU47_RS06100 WP_000106346.1 1138785..1140017(+) (clpX) [Streptococcus pneumoniae strain NP2]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A064C077

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.585

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.214

98.049

0.561