Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   OTU47_RS00410 Genome accession   NZ_CP113115
Coordinates   71158..71847 (-) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NP2     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 66158..76847
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTU47_RS00385 (OTU47_00385) - 66833..67162 (-) 330 WP_000196971.1 transposase -
  OTU47_RS00390 (OTU47_00390) - 67824..68162 (+) 339 WP_001820155.1 lanthionine synthetase LanC family protein -
  OTU47_RS00395 (OTU47_00395) - 68062..68532 (+) 471 WP_055349284.1 lanthionine synthetase LanC family protein -
  OTU47_RS00400 (OTU47_00400) - 68691..69923 (+) 1233 WP_000765686.1 MFS transporter -
  OTU47_RS00405 (OTU47_00405) cbpC 70041..71060 (-) 1020 WP_050117920.1 choline-binding protein CbpC -
  OTU47_RS00410 (OTU47_00410) covR 71158..71847 (-) 690 WP_000518011.1 response regulator transcription factor Regulator
  OTU47_RS00415 (OTU47_00415) gndA 71859..73283 (-) 1425 WP_000158776.1 NADP-dependent phosphogluconate dehydrogenase -
  OTU47_RS00420 (OTU47_00420) mapZ 73359..74753 (-) 1395 WP_000039275.1 cell division site-positioning protein MapZ -
  OTU47_RS00425 (OTU47_00425) - 74766..75923 (-) 1158 WP_050117921.1 class I SAM-dependent RNA methyltransferase -
  OTU47_RS00435 (OTU47_00435) gpsB 76409..76738 (-) 330 WP_000146522.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=760386 OTU47_RS00410 WP_000518011.1 71158..71847(-) (covR) [Streptococcus pneumoniae strain NP2]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=760386 OTU47_RS00410 WP_000518011.1 71158..71847(-) (covR) [Streptococcus pneumoniae strain NP2]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGTAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTCTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGACAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467