Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   OTU45_RS02280 Genome accession   NZ_CP113114
Coordinates   453848..454537 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NP1     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 448848..459537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTU45_RS02255 (OTU45_02255) gpsB 448957..449286 (+) 330 WP_000146522.1 cell division regulator GpsB -
  OTU45_RS02265 (OTU45_02265) - 449772..450929 (+) 1158 WP_050117921.1 class I SAM-dependent RNA methyltransferase -
  OTU45_RS02270 (OTU45_02270) mapZ 450942..452336 (+) 1395 WP_000039275.1 cell division site-positioning protein MapZ -
  OTU45_RS02275 (OTU45_02275) gndA 452412..453836 (+) 1425 WP_000158776.1 NADP-dependent phosphogluconate dehydrogenase -
  OTU45_RS02280 (OTU45_02280) covR 453848..454537 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  OTU45_RS02285 (OTU45_02285) cbpC 454635..455654 (+) 1020 WP_050117920.1 choline-binding protein CbpC -
  OTU45_RS02290 (OTU45_02290) - 455772..457004 (-) 1233 WP_000765686.1 MFS transporter -
  OTU45_RS02295 (OTU45_02295) - 457163..457633 (-) 471 WP_055349284.1 lanthionine synthetase LanC family protein -
  OTU45_RS02300 (OTU45_02300) - 457533..457871 (-) 339 WP_001820155.1 lanthionine synthetase LanC family protein -
  OTU45_RS02305 (OTU45_02305) - 458533..458700 (+) 168 Protein_448 transposase -
  OTU45_RS02310 (OTU45_02310) - 458740..458862 (+) 123 Protein_449 hypothetical protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=760321 OTU45_RS02280 WP_000518011.1 453848..454537(+) (covR) [Streptococcus pneumoniae strain NP1]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=760321 OTU45_RS02280 WP_000518011.1 453848..454537(+) (covR) [Streptococcus pneumoniae strain NP1]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGTAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTCTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGACAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467