Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   OTU45_RS00085 Genome accession   NZ_CP113114
Coordinates   15374..16036 (-) Length   220 a.a.
NCBI ID   WP_000649978.1    Uniprot ID   A0A0E8ARN2
Organism   Streptococcus pneumoniae strain NP1     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 10374..21036
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTU45_RS00060 (OTU45_00060) - 10525..10791 (-) 267 WP_044814445.1 Veg family protein -
  OTU45_RS00065 (OTU45_00065) dnaB 10793..12145 (-) 1353 WP_000852486.1 replicative DNA helicase -
  OTU45_RS00070 (OTU45_00070) rplI 12188..12640 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  OTU45_RS00075 (OTU45_00075) - 12637..14610 (-) 1974 WP_000715109.1 DHH family phosphoesterase -
  OTU45_RS00080 (OTU45_00080) hpf 14746..15294 (-) 549 WP_000599104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  OTU45_RS00085 (OTU45_00085) comFC/cflB 15374..16036 (-) 663 WP_000649978.1 ComF family protein Machinery gene
  OTU45_RS00090 (OTU45_00090) comFA/cflA 16033..17331 (-) 1299 WP_000867612.1 DEAD/DEAH box helicase Machinery gene
  OTU45_RS00095 (OTU45_00095) - 17387..18022 (+) 636 WP_000395739.1 YigZ family protein -
  OTU45_RS00100 (OTU45_00100) cysK 18307..19227 (+) 921 WP_000029869.1 cysteine synthase A -
  OTU45_RS00105 (OTU45_00105) - 19466..19840 (-) 375 Protein_20 IS66 family transposase -
  OTU45_RS00110 (OTU45_00110) - 19813..20100 (+) 288 Protein_21 transposase -
  OTU45_RS00115 (OTU45_00115) tnpB 20255..20470 (-) 216 WP_235786183.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25240.11 Da        Isoelectric Point: 7.7116

>NTDB_id=760307 OTU45_RS00085 WP_000649978.1 15374..16036(-) (comFC/cflB) [Streptococcus pneumoniae strain NP1]
MKCLLCGQTMKTVLTFSSLLLLRNNDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=760307 OTU45_RS00085 WP_000649978.1 15374..16036(-) (comFC/cflB) [Streptococcus pneumoniae strain NP1]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATAATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E8ARN2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae Rx1

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae D39

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae R6

99.091

100

0.991
  comFC/cflB Streptococcus mitis NCTC 12261

91.364

100

0.914
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909