Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   H7R23_RS17815 Genome accession   NZ_AP021936
Coordinates   3720964..3722190 (+) Length   408 a.a.
NCBI ID   WP_017481950.1    Uniprot ID   A0A6S4UPK2
Organism   Acinetobacter pittii strain WP2-W18-ESBL-11     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3715964..3727190
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7R23_RS17780 (WP2W18E11_34800) rimP 3716634..3717158 (-) 525 WP_002114922.1 ribosome maturation factor RimP -
  H7R23_RS17800 (WP2W18E11_34810) secG 3717796..3718125 (-) 330 WP_002115012.1 preprotein translocase subunit SecG -
  H7R23_RS17805 (WP2W18E11_34820) tpiA 3718138..3718932 (-) 795 WP_017481951.1 triose-phosphate isomerase -
  H7R23_RS17810 (WP2W18E11_34830) pilB 3719225..3720937 (+) 1713 WP_017385371.1 type IV-A pilus assembly ATPase PilB Machinery gene
  H7R23_RS17815 (WP2W18E11_34840) pilC 3720964..3722190 (+) 1227 WP_017481950.1 type II secretion system F family protein Machinery gene
  H7R23_RS17820 (WP2W18E11_34850) pilD 3722190..3723050 (+) 861 WP_017481949.1 prepilin peptidase Machinery gene
  H7R23_RS17825 (WP2W18E11_34860) coaE 3723052..3723648 (+) 597 WP_017398727.1 dephospho-CoA kinase -
  H7R23_RS17830 (WP2W18E11_34870) - 3723645..3724559 (-) 915 WP_017398726.1 DMT family transporter -
  H7R23_RS17835 (WP2W18E11_34880) rlmB 3724595..3725344 (-) 750 WP_005079348.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  H7R23_RS17840 (WP2W18E11_34890) - 3725447..3725773 (-) 327 WP_002115102.1 pyrimidine/purine nucleoside phosphorylase -
  H7R23_RS17845 (WP2W18E11_34900) - 3725850..3727160 (-) 1311 WP_017481948.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45056.49 Da        Isoelectric Point: 9.8960

>NTDB_id=75993 H7R23_RS17815 WP_017481950.1 3720964..3722190(+) (pilC) [Acinetobacter pittii strain WP2-W18-ESBL-11]
MTVKKAQMMPTFAYEGVDRKGVKIKGELPAKNMALAKVTLRKQGVTVRNIREKRKNILEGLFKKKVSTLDITIFTRQLAT
MMKAGVPLVQGFEIVAEGLENPAMREVVLGIKGEVESGSTFASALRKYPQHFDNLFCSLVESGEQSGALETMLDRVAIYK
EKSELLKQKIKKAMKYPATVIVVAVIVTIILMVKVVPVFQDLFSSFGADLPAFTQMVVNMSKWMQEYWFIMIIAIGAVIA
AFLEAKKRSKKFRDGLDKLTLKLPIFGDLVYKAIIARYSRTLATTFAAGVPLIDALESTAGATNNIIYEQAVMKIREDVA
TGQQLQFAMRVSNRFPSMAIQMVAIGEESGALDSMLDKVATYYENEVDNAVDGLTSMMEPLIMAILGVLVGGLVIAMYLP
IFQMGSVI

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=75993 H7R23_RS17815 WP_017481950.1 3720964..3722190(+) (pilC) [Acinetobacter pittii strain WP2-W18-ESBL-11]
ATGACTGTCAAAAAGGCACAAATGATGCCGACTTTTGCTTATGAAGGGGTTGACCGTAAGGGCGTAAAAATTAAGGGCGA
ACTTCCGGCTAAGAATATGGCCTTAGCCAAAGTCACCCTACGCAAACAAGGGGTAACTGTCCGTAATATTCGAGAAAAGC
GTAAAAATATTCTTGAAGGTTTATTCAAGAAGAAAGTATCCACACTCGATATCACGATTTTCACCCGTCAACTTGCAACG
ATGATGAAAGCAGGGGTTCCACTGGTACAAGGCTTTGAAATTGTAGCGGAAGGTCTAGAAAACCCTGCTATGCGCGAGGT
GGTACTCGGGATTAAAGGCGAAGTTGAAAGTGGTAGTACCTTTGCTTCAGCTTTAAGAAAGTATCCTCAACACTTCGATA
ACTTGTTTTGTTCTCTTGTAGAGTCTGGTGAACAATCTGGTGCGCTTGAAACCATGTTGGACCGCGTGGCAATTTACAAA
GAAAAAAGTGAATTACTTAAGCAGAAAATCAAAAAAGCTATGAAATATCCCGCAACGGTTATTGTGGTTGCTGTGATTGT
TACCATTATTTTGATGGTTAAAGTTGTTCCGGTTTTCCAAGACCTGTTTTCTTCTTTTGGCGCAGATTTACCTGCATTTA
CCCAAATGGTCGTGAATATGTCGAAATGGATGCAGGAATACTGGTTTATTATGATTATTGCCATTGGAGCAGTCATTGCT
GCCTTTCTGGAAGCCAAGAAGCGTAGTAAAAAATTCCGCGATGGTTTAGACAAACTCACACTGAAACTACCTATCTTCGG
TGATCTGGTTTATAAGGCGATTATTGCCCGTTATAGCCGTACTTTAGCCACCACGTTTGCCGCTGGTGTTCCGCTCATTG
ATGCGCTTGAGTCAACAGCTGGTGCAACCAACAATATTATTTATGAACAAGCAGTGATGAAAATTCGTGAAGATGTTGCT
ACAGGCCAACAACTCCAATTTGCAATGCGTGTTTCAAATCGTTTTCCATCGATGGCTATACAAATGGTCGCAATTGGTGA
AGAATCTGGTGCACTAGACAGCATGCTCGATAAAGTTGCCACTTATTATGAAAATGAAGTTGATAATGCCGTTGATGGTT
TAACTTCTATGATGGAACCTTTAATTATGGCAATTTTAGGGGTGCTCGTAGGTGGTCTAGTGATTGCTATGTATCTTCCA
ATTTTCCAAATGGGCTCAGTCATATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(74-197)

Type II secretion system (T2SS), protein F (T2SSF)

(279-400)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6S4UPK2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Acinetobacter baumannii D1279779

97.304

100

0.973
  pilC Acinetobacter baylyi ADP1

85.049

100

0.85
  pilC Pseudomonas stutzeri DSM 10701

59.506

99.265

0.591
  pilC Legionella pneumophila strain ERS1305867

53.333

99.265

0.529
  pilG Neisseria gonorrhoeae MS11

46.231

97.549

0.451
  pilG Neisseria meningitidis 44/76-A

46.231

97.549

0.451
  pilC Vibrio cholerae strain A1552

42.402

100

0.424
  pilC Vibrio campbellii strain DS40M4

41.089

99.02

0.407
  pilC Thermus thermophilus HB27

36.658

98.284

0.36

Multiple sequence alignment