Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   OS084_RS13350 Genome accession   NZ_CP113052
Coordinates   2641611..2642297 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain Fizz     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2636611..2647297
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS084_RS13330 rpsT 2637525..2637776 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  OS084_RS13335 holA 2637821..2638795 (-) 975 WP_001282562.1 DNA polymerase III subunit delta -
  OS084_RS13340 comEC 2638852..2641053 (-) 2202 WP_001548978.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  OS084_RS13345 - 2641058..2641519 (-) 462 WP_000439693.1 ComE operon protein 2 -
  OS084_RS13350 comEA 2641611..2642297 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  OS084_RS13355 - 2642337..2643053 (-) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  OS084_RS13360 rsfS 2643056..2643409 (-) 354 WP_001088022.1 ribosome silencing factor -
  OS084_RS13365 yqeK 2643410..2643994 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  OS084_RS13370 nadD 2643984..2644553 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  OS084_RS13375 yhbY 2644556..2644846 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  OS084_RS13380 aroE 2644850..2645656 (-) 807 WP_267837996.1 shikimate dehydrogenase -
  OS084_RS13385 yqeH 2645670..2646770 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=759643 OS084_RS13350 WP_001792568.1 2641611..2642297(-) (comEA) [Staphylococcus aureus strain Fizz]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=759643 OS084_RS13350 WP_001792568.1 2641611..2642297(-) (comEA) [Staphylococcus aureus strain Fizz]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969