Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   OS085_RS07350 Genome accession   NZ_CP113044
Coordinates   1460567..1461136 (+) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain LeBlanc     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1455567..1466136
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS085_RS07325 cysE 1456780..1457427 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  OS085_RS07330 cysS 1457411..1458811 (+) 1401 WP_000631963.1 cysteine--tRNA ligase -
  OS085_RS07335 - 1458804..1459208 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  OS085_RS07340 rlmB 1459216..1459962 (+) 747 WP_267836482.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  OS085_RS07345 - 1459962..1460486 (+) 525 WP_000664738.1 NYN domain-containing protein -
  OS085_RS07350 sigH 1460567..1461136 (+) 570 WP_000872873.1 sigma-70 family RNA polymerase sigma factor Regulator
  OS085_RS07355 rpmG 1461251..1461394 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  OS085_RS07360 secE 1461450..1461632 (+) 183 WP_001074474.1 preprotein translocase subunit SecE -
  OS085_RS07365 nusG 1461645..1462193 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  OS085_RS07370 rplK 1462374..1462796 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  OS085_RS07375 rplA 1463004..1463696 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  OS085_RS07380 rplJ 1463968..1464468 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  OS085_RS07385 rplL 1464511..1464879 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  OS085_RS07390 - 1465054..1465662 (+) 609 WP_267810988.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=759452 OS085_RS07350 WP_000872873.1 1460567..1461136(+) (sigH) [Staphylococcus aureus strain LeBlanc]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=759452 OS085_RS07350 WP_000872873.1 1460567..1461136(+) (sigH) [Staphylococcus aureus strain LeBlanc]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984