Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   OS079_RS13235 Genome accession   NZ_CP113042
Coordinates   2624745..2625431 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain Seraphine     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2619745..2630431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS079_RS13215 rpsT 2620659..2620910 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  OS079_RS13220 holA 2620955..2621929 (-) 975 WP_001282562.1 DNA polymerase III subunit delta -
  OS079_RS13225 comEC 2621986..2624187 (-) 2202 WP_267837927.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  OS079_RS13230 - 2624192..2624653 (-) 462 WP_000439693.1 ComE operon protein 2 -
  OS079_RS13235 comEA 2624745..2625431 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  OS079_RS13240 - 2625471..2626187 (-) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  OS079_RS13245 rsfS 2626190..2626543 (-) 354 WP_001088022.1 ribosome silencing factor -
  OS079_RS13250 yqeK 2626544..2627128 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  OS079_RS13255 nadD 2627118..2627687 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  OS079_RS13260 yhbY 2627690..2627980 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  OS079_RS13265 aroE 2627984..2628790 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  OS079_RS13270 yqeH 2628804..2629904 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=759429 OS079_RS13235 WP_001792568.1 2624745..2625431(-) (comEA) [Staphylococcus aureus strain Seraphine]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=759429 OS079_RS13235 WP_001792568.1 2624745..2625431(-) (comEA) [Staphylococcus aureus strain Seraphine]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969