Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   OS086_RS14335 Genome accession   NZ_CP113039
Coordinates   2846136..2846822 (-) Length   228 a.a.
NCBI ID   WP_001802022.1    Uniprot ID   A0A7U7EYP5
Organism   Staphylococcus aureus strain Gwen     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2841136..2851822
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS086_RS14315 rpsT 2842050..2842301 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  OS086_RS14320 holA 2842346..2843320 (-) 975 WP_001282563.1 DNA polymerase III subunit delta -
  OS086_RS14325 comEC 2843377..2845578 (-) 2202 WP_001557362.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  OS086_RS14330 - 2845583..2846044 (-) 462 WP_000439693.1 ComE operon protein 2 -
  OS086_RS14335 comEA 2846136..2846822 (-) 687 WP_001802022.1 ComEA family DNA-binding protein Machinery gene
  OS086_RS14340 - 2846862..2847578 (-) 717 WP_000084830.1 class I SAM-dependent DNA methyltransferase -
  OS086_RS14345 rsfS 2847581..2847934 (-) 354 WP_001088020.1 ribosome silencing factor -
  OS086_RS14350 yqeK 2847935..2848519 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  OS086_RS14355 nadD 2848509..2849078 (-) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  OS086_RS14360 yhbY 2849081..2849371 (-) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  OS086_RS14365 aroE 2849375..2850181 (-) 807 WP_000666757.1 shikimate dehydrogenase -
  OS086_RS14370 yqeH 2850195..2851295 (-) 1101 WP_001280137.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25900.65 Da        Isoelectric Point: 9.6751

>NTDB_id=759392 OS086_RS14335 WP_001802022.1 2846136..2846822(-) (comEA) [Staphylococcus aureus strain Gwen]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=759392 OS086_RS14335 WP_001802022.1 2846136..2846822(-) (comEA) [Staphylococcus aureus strain Gwen]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAATAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCGAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EYP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus N315

100

100

1
  comEA Staphylococcus aureus MW2

97.368

100

0.974