Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   OS086_RS08770 Genome accession   NZ_CP113039
Coordinates   1731879..1732448 (+) Length   189 a.a.
NCBI ID   WP_000872882.1    Uniprot ID   A0A7U7EXA1
Organism   Staphylococcus aureus strain Gwen     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1726879..1737448
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS086_RS08745 cysE 1728092..1728739 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  OS086_RS08750 cysS 1728723..1730123 (+) 1401 WP_000631969.1 cysteine--tRNA ligase -
  OS086_RS08755 - 1730116..1730520 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  OS086_RS08760 rlmB 1730528..1731274 (+) 747 WP_267810987.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  OS086_RS08765 - 1731274..1731798 (+) 525 WP_000664737.1 NYN domain-containing protein -
  OS086_RS08770 sigH 1731879..1732448 (+) 570 WP_000872882.1 sigma-70 family RNA polymerase sigma factor Regulator
  OS086_RS08775 rpmG 1732563..1732706 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  OS086_RS08780 secE 1732762..1732944 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  OS086_RS08785 nusG 1732957..1733505 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  OS086_RS08790 rplK 1733686..1734108 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  OS086_RS08795 rplA 1734316..1735008 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  OS086_RS08800 rplJ 1735280..1735780 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  OS086_RS08805 rplL 1735823..1736191 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  OS086_RS08810 - 1736366..1736974 (+) 609 WP_267810988.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23044.91 Da        Isoelectric Point: 9.4170

>NTDB_id=759373 OS086_RS08770 WP_000872882.1 1731879..1732448(+) (sigH) [Staphylococcus aureus strain Gwen]
MKYDLTTQDSTIKRNNSINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=759373 OS086_RS08770 WP_000872882.1 1731879..1732448(+) (sigH) [Staphylococcus aureus strain Gwen]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATTCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXA1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

100

100

1
  sigH Staphylococcus aureus MW2

97.884

100

0.979