Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   OS080_RS08445 Genome accession   NZ_CP113032
Coordinates   1671922..1672608 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain Akali     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1666922..1677608
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS080_RS08425 rpsT 1667836..1668087 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  OS080_RS08430 holA 1668132..1669106 (-) 975 WP_001282562.1 DNA polymerase III subunit delta -
  OS080_RS08435 comEC 1669163..1671364 (-) 2202 WP_001807336.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  OS080_RS08440 - 1671369..1671830 (-) 462 WP_000439693.1 ComE operon protein 2 -
  OS080_RS08445 comEA 1671922..1672608 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  OS080_RS08450 - 1672648..1673364 (-) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  OS080_RS08455 rsfS 1673367..1673720 (-) 354 WP_001088022.1 ribosome silencing factor -
  OS080_RS08460 yqeK 1673721..1674305 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  OS080_RS08465 nadD 1674295..1674864 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  OS080_RS08470 yhbY 1674867..1675157 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  OS080_RS08475 aroE 1675161..1675967 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  OS080_RS08480 yqeH 1675981..1677081 (-) 1101 WP_001280148.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=759290 OS080_RS08445 WP_001792568.1 1671922..1672608(-) (comEA) [Staphylococcus aureus strain Akali]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=759290 OS080_RS08445 WP_001792568.1 1671922..1672608(-) (comEA) [Staphylococcus aureus strain Akali]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969