Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | OS090_RS01505 | Genome accession | NZ_CP113018 |
| Coordinates | 289428..291056 (+) | Length | 542 a.a. |
| NCBI ID | WP_001186596.1 | Uniprot ID | - |
| Organism | Staphylococcus aureus strain Taliyah | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 288061..354998 | 289428..291056 | within | 0 |
Gene organization within MGE regions
Location: 288061..354998
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OS090_RS01500 | ccrA | 288061..289407 (+) | 1347 | WP_000816499.1 | cassette chromosome recombinase CcrA | Machinery gene |
| OS090_RS01505 | ccrB | 289428..291056 (+) | 1629 | WP_001186596.1 | cassette chromosome recombinase CcrB | Machinery gene |
| OS090_RS01510 | - | 291527..291877 (+) | 351 | WP_000171449.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| OS090_RS01515 | - | 291962..292273 (+) | 312 | WP_000833212.1 | DUF960 family protein | - |
| OS090_RS01520 | - | 292292..292813 (+) | 522 | WP_000836008.1 | DUF1643 domain-containing protein | - |
| OS090_RS01525 | - | 292815..293021 (+) | 207 | WP_001077283.1 | hypothetical protein | - |
| OS090_RS01530 | - | 293014..293337 (+) | 324 | WP_000088091.1 | JAB domain-containing protein | - |
| OS090_RS01535 | - | 293532..295424 (+) | 1893 | Protein_268 | site-specific integrase | - |
| OS090_RS01540 | - | 295431..295808 (+) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| OS090_RS01545 | - | 295959..296741 (+) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| OS090_RS01550 | erm(A) | 296867..297598 (-) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| OS090_RS16660 | - | 297612..297713 (-) | 102 | WP_418896053.1 | erythromycin resistance leader peptide | - |
| OS090_RS01555 | - | 298105..298767 (+) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| OS090_RS01560 | - | 298999..299145 (+) | 147 | Protein_274 | JAB domain-containing protein | - |
| OS090_RS01565 | - | 299315..300187 (+) | 873 | WP_000373151.1 | HTH domain-containing protein | - |
| OS090_RS01570 | - | 300244..300534 (+) | 291 | WP_000065262.1 | hypothetical protein | - |
| OS090_RS01575 | - | 300550..301038 (+) | 489 | WP_000397419.1 | hypothetical protein | - |
| OS090_RS01580 | - | 301173..301700 (+) | 528 | WP_000717928.1 | hypothetical protein | - |
| OS090_RS01585 | - | 301763..302179 (+) | 417 | WP_000941331.1 | hypothetical protein | - |
| OS090_RS01590 | - | 302468..302632 (+) | 165 | WP_001803222.1 | hypothetical protein | - |
| OS090_RS01595 | - | 302646..302867 (+) | 222 | WP_001070883.1 | hypothetical protein | - |
| OS090_RS01600 | - | 303017..303583 (+) | 567 | WP_000759939.1 | PepSY domain-containing protein | - |
| OS090_RS01605 | - | 303663..305876 (-) | 2214 | Protein_283 | type I restriction endonuclease subunit R | - |
| OS090_RS01610 | - | 305938..306612 (-) | 675 | WP_001105999.1 | IS6-like element IS257 family transposase | - |
| OS090_RS01615 | - | 306895..308241 (+) | 1347 | WP_064221817.1 | dihydrolipoyl dehydrogenase family protein | - |
| OS090_RS01620 | merR | 308541..308948 (+) | 408 | WP_000425271.1 | Hg(II)-responsive transcriptional regulator MerR | - |
| OS090_RS01625 | - | 308965..309318 (+) | 354 | WP_000746201.1 | TlpA family protein disulfide reductase | - |
| OS090_RS01630 | - | 309315..309995 (+) | 681 | WP_000010352.1 | cytochrome c biogenesis CcdA family protein | - |
| OS090_RS01635 | merT | 310083..310469 (+) | 387 | WP_001794630.1 | mercuric transport protein MerT | - |
| OS090_RS01640 | merA | 310527..312170 (+) | 1644 | WP_000193219.1 | mercury(II) reductase | - |
| OS090_RS01645 | merB | 312252..312902 (+) | 651 | WP_000790333.1 | organomercurial lyase MerB | - |
| OS090_RS01650 | - | 313097..313612 (-) | 516 | WP_000377078.1 | hypothetical protein | - |
| OS090_RS01655 | - | 313731..314405 (-) | 675 | WP_001105988.1 | IS6-like element IS257 family transposase | - |
| OS090_RS01660 | - | 314441..314830 (+) | 390 | WP_020444595.1 | hydroxymethylglutaryl-CoA synthase | - |
| OS090_RS01665 | - | 315907..316650 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| OS090_RS01670 | - | 316747..317175 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| OS090_RS01675 | mecA | 317221..319230 (-) | 2010 | WP_267790023.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| OS090_RS01680 | mecR1 | 319327..321084 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| OS090_RS01685 | mecI | 321084..321455 (+) | 372 | Protein_299 | mecA-type methicillin resistance repressor MecI | - |
| OS090_RS01690 | psm-mec | 321540..321608 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| OS090_RS01695 | - | 321928..323076 (+) | 1149 | WP_000427807.1 | ROK family transcriptional regulator | - |
| OS090_RS01700 | cstB | 323190..324524 (-) | 1335 | Protein_302 | persulfide dioxygenase-sulfurtransferase CstB | - |
| OS090_RS01705 | - | 324556..325620 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| OS090_RS01710 | cstR | 325756..326016 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| OS090_RS01715 | - | 326016..326654 (+) | 639 | Protein_305 | sulfite exporter TauE/SafE family protein | - |
| OS090_RS01720 | - | 326928..327545 (-) | 618 | WP_000562107.1 | CadD family cadmium resistance transporter | - |
| OS090_RS01725 | - | 327626..330040 (-) | 2415 | WP_000378485.1 | cadmium-translocating P-type ATPase CadA | - |
| OS090_RS01730 | - | 330033..330398 (-) | 366 | WP_000159127.1 | ArsR/SmtB family transcription factor | - |
| OS090_RS01735 | - | 330584..330961 (-) | 378 | WP_001041908.1 | DUF6262 family protein | - |
| OS090_RS01740 | - | 330968..332860 (-) | 1893 | WP_014532403.1 | site-specific integrase | - |
| OS090_RS01745 | - | 332857..333942 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| OS090_RS01750 | - | 334061..334378 (-) | 318 | WP_023180038.1 | JAB domain-containing protein | - |
| OS090_RS01755 | - | 334399..334905 (-) | 507 | WP_000848380.1 | DUF1643 domain-containing protein | - |
| OS090_RS01760 | - | 334921..335232 (-) | 312 | WP_001166716.1 | DUF960 family protein | - |
| OS090_RS01765 | - | 335326..335664 (-) | 339 | WP_000175892.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| OS090_RS01770 | tnpA | 335956..336441 (-) | 486 | WP_000093392.1 | IS200/IS605 family transposase | - |
| OS090_RS01775 | ccrC | 336489..338174 (-) | 1686 | WP_000676600.1 | cassette chromosome recombinase CcrC | - |
| OS090_RS01780 | - | 338399..340042 (-) | 1644 | WP_267789990.1 | DUF5906 domain-containing protein | - |
| OS090_RS01785 | - | 340039..340410 (-) | 372 | WP_001058157.1 | hypothetical protein | - |
| OS090_RS01790 | - | 340403..341503 (-) | 1101 | WP_000449985.1 | DNA polymerase | - |
| OS090_RS01795 | - | 341730..343204 (-) | 1475 | Protein_321 | DUF6038 family protein | - |
| OS090_RS01800 | - | 343312..344175 (-) | 864 | WP_000680579.1 | LEM-3-like GIY-YIG domain-containing protein | - |
| OS090_RS01805 | - | 344373..344678 (-) | 306 | WP_000677987.1 | hypothetical protein | - |
| OS090_RS01810 | - | 345147..345692 (-) | 546 | WP_000592151.1 | YdhK family protein | - |
| OS090_RS01815 | - | 345710..345919 (-) | 210 | Protein_325 | heavy metal translocating P-type ATPase | - |
| OS090_RS01820 | - | 346089..346848 (-) | 760 | Protein_326 | sulfite exporter TauE/SafE family protein | - |
| OS090_RS01825 | cstR | 346845..347106 (-) | 262 | Protein_327 | persulfide-sensing transcriptional repressor CstR | - |
| OS090_RS01830 | - | 347245..348312 (+) | 1068 | WP_267793757.1 | DsrE/DsrF/DrsH-like family protein | - |
| OS090_RS01835 | cstB | 348331..349660 (+) | 1330 | Protein_329 | persulfide dioxygenase-sulfurtransferase CstB | - |
| OS090_RS01840 | - | 349883..350884 (+) | 1002 | WP_070678289.1 | hypothetical protein | - |
| OS090_RS01845 | ssb | 351064..351357 (+) | 294 | WP_070678286.1 | cassette chromosome ssDNA-binding protein | - |
| OS090_RS01850 | cch1 | 351354..353147 (+) | 1794 | WP_418896070.1 | cassette chromosome replicative helicase | - |
| OS090_RS01855 | - | 353215..353472 (+) | 258 | WP_070840097.1 | hypothetical protein | - |
| OS090_RS01860 | ccrA | 353649..354998 (+) | 1350 | WP_267793758.1 | cassette chromosome recombinase CcrA | Machinery gene |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62274.15 Da Isoelectric Point: 9.7334
>NTDB_id=759134 OS090_RS01505 WP_001186596.1 289428..291056(+) (ccrB) [Staphylococcus aureus strain Taliyah]
MQQLKQKRVGIYVRVSTEIQSTEGYSIDGQINQIREYCDFNNFVVVDVYADRGISGKSMNRPELQRLLKDANEGQIDSVM
VYKTNRLARNTSDLLKIVEDLHRQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSIGSVTYILSNPFYVGKIQFAK
YKDWNEKRRKGLNDKPIIAEGKHSPIIIQDLWDKVQLRKKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVINQVLERVNQENKVDIGALNHDIAYKQQQYD
EVSGKLHNLVKTIEDNPDLTSALKATIHQYETQLNDITNQMNQLKQQQNQEKLSYDTKQIAALLQRIFQNIESMDKAQLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTPLDEVLLSTSSLFLPQTLFLQI
MQQLKQKRVGIYVRVSTEIQSTEGYSIDGQINQIREYCDFNNFVVVDVYADRGISGKSMNRPELQRLLKDANEGQIDSVM
VYKTNRLARNTSDLLKIVEDLHRQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSIGSVTYILSNPFYVGKIQFAK
YKDWNEKRRKGLNDKPIIAEGKHSPIIIQDLWDKVQLRKKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVINQVLERVNQENKVDIGALNHDIAYKQQQYD
EVSGKLHNLVKTIEDNPDLTSALKATIHQYETQLNDITNQMNQLKQQQNQEKLSYDTKQIAALLQRIFQNIESMDKAQLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTPLDEVLLSTSSLFLPQTLFLQI
Nucleotide
Download Length: 1629 bp
>NTDB_id=759134 OS090_RS01505 WP_001186596.1 289428..291056(+) (ccrB) [Staphylococcus aureus strain Taliyah]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATCCAAAGTACTGAAGGCTATAGTAT
CGATGGACAAATCAATCAAATTCGAGAATATTGTGATTTCAATAACTTTGTTGTTGTAGATGTATACGCGGATAGAGGTA
TCTCTGGAAAATCTATGAACCGACCAGAACTACAACGTTTGTTAAAAGATGCGAACGAAGGTCAGATTGATTCTGTTATG
GTCTACAAAACAAACCGACTAGCACGTAACACTTCTGACTTACTCAAAATTGTTGAAGACCTTCATCGTCAAAATGTCGA
ATTCTTCAGCTTATCTGAGCGTATGGAAGTCAATACAAGCAGTGGTAAATTGATGCTACAAATTCTAGCGAGTTTTTCAG
AATTTGAAAGAAATAATATTGTCGAAAATGTATTCATGGGTCAAACCCGACGCGCTCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCGGATAGCAAGCATGAACTCATGATAAACCAACATGAAGCGAATATTGTCAAATA
TATATTTGAGTCATATGCTAAAGGCCACGGATATCGTAAAATTGCGAATGCACTCAATCACAAAGGATACGTGACTAAAA
AAGGAAAGCCTTTCAGTATTGGTTCAGTGACCTATATCTTATCTAATCCATTCTATGTTGGTAAAATTCAATTCGCAAAG
TACAAAGATTGGAATGAAAAGCGTCGTAAAGGGCTGAATGATAAACCAATAATAGCTGAAGGTAAGCATTCCCCTATTAT
TATTCAAGACTTATGGGATAAAGTCCAATTACGTAAAAAACAAGTCAGTCAAAAACCTCAAGTCCACGGTAAAGGAACTA
ATCTATTAACAGGTATCGTTCATTGTCCACAATGTGGTGCACCAATGGCAGCTAGTAACACAACGAACACATTGAAAGAT
GGTACCAAGAAGCGAATACGTTATTATTCTTGCAGTAACTTCCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGCGT
TAGAGCTGATGTGATTGAAAAATACGTCATGGATCAAATACTCGAAATTGTCAAAAGTGATAAAGTCATTAACCAAGTCT
TAGAACGTGTCAATCAAGAAAATAAAGTCGATATTGGTGCATTGAACCACGATATCGCTTATAAACAACAACAATACGAT
GAAGTCAGCGGGAAACTCCATAATTTAGTTAAAACCATTGAAGATAATCCGGACCTAACATCTGCATTGAAAGCAACTAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAACTCAAACAGCAACAAAATCAAGAGAAACTAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATCAATGGATAAAGCACAACTCAAA
GCATTATATCTTACAGTCATTGACCGTATTGATATTCGTAAAGACGGTAATCATAAAAAACAGTTCTACGTTACACTAAA
ACTCAATAATGAAATTATTAAACAACTTTTCAATAATACCCCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACGCTCTTTCTTCAAATCTAA
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATCCAAAGTACTGAAGGCTATAGTAT
CGATGGACAAATCAATCAAATTCGAGAATATTGTGATTTCAATAACTTTGTTGTTGTAGATGTATACGCGGATAGAGGTA
TCTCTGGAAAATCTATGAACCGACCAGAACTACAACGTTTGTTAAAAGATGCGAACGAAGGTCAGATTGATTCTGTTATG
GTCTACAAAACAAACCGACTAGCACGTAACACTTCTGACTTACTCAAAATTGTTGAAGACCTTCATCGTCAAAATGTCGA
ATTCTTCAGCTTATCTGAGCGTATGGAAGTCAATACAAGCAGTGGTAAATTGATGCTACAAATTCTAGCGAGTTTTTCAG
AATTTGAAAGAAATAATATTGTCGAAAATGTATTCATGGGTCAAACCCGACGCGCTCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCGGATAGCAAGCATGAACTCATGATAAACCAACATGAAGCGAATATTGTCAAATA
TATATTTGAGTCATATGCTAAAGGCCACGGATATCGTAAAATTGCGAATGCACTCAATCACAAAGGATACGTGACTAAAA
AAGGAAAGCCTTTCAGTATTGGTTCAGTGACCTATATCTTATCTAATCCATTCTATGTTGGTAAAATTCAATTCGCAAAG
TACAAAGATTGGAATGAAAAGCGTCGTAAAGGGCTGAATGATAAACCAATAATAGCTGAAGGTAAGCATTCCCCTATTAT
TATTCAAGACTTATGGGATAAAGTCCAATTACGTAAAAAACAAGTCAGTCAAAAACCTCAAGTCCACGGTAAAGGAACTA
ATCTATTAACAGGTATCGTTCATTGTCCACAATGTGGTGCACCAATGGCAGCTAGTAACACAACGAACACATTGAAAGAT
GGTACCAAGAAGCGAATACGTTATTATTCTTGCAGTAACTTCCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGCGT
TAGAGCTGATGTGATTGAAAAATACGTCATGGATCAAATACTCGAAATTGTCAAAAGTGATAAAGTCATTAACCAAGTCT
TAGAACGTGTCAATCAAGAAAATAAAGTCGATATTGGTGCATTGAACCACGATATCGCTTATAAACAACAACAATACGAT
GAAGTCAGCGGGAAACTCCATAATTTAGTTAAAACCATTGAAGATAATCCGGACCTAACATCTGCATTGAAAGCAACTAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAACTCAAACAGCAACAAAATCAAGAGAAACTAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATCAATGGATAAAGCACAACTCAAA
GCATTATATCTTACAGTCATTGACCGTATTGATATTCGTAAAGACGGTAATCATAAAAAACAGTTCTACGTTACACTAAA
ACTCAATAATGAAATTATTAAACAACTTTTCAATAATACCCCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACGCTCTTTCTTCAAATCTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
86.531 |
100 |
0.865 |