Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   OS078_RS11985 Genome accession   NZ_CP113015
Coordinates   2378424..2379110 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain Zed     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2373424..2384110
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS078_RS11965 rpsT 2374338..2374589 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  OS078_RS11970 holA 2374634..2375608 (-) 975 WP_001282562.1 DNA polymerase III subunit delta -
  OS078_RS11975 comEC 2375665..2377866 (-) 2202 WP_001807336.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  OS078_RS11980 - 2377871..2378332 (-) 462 WP_000439693.1 ComE operon protein 2 -
  OS078_RS11985 comEA 2378424..2379110 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  OS078_RS11990 - 2379150..2379866 (-) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  OS078_RS11995 rsfS 2379869..2380222 (-) 354 WP_001088022.1 ribosome silencing factor -
  OS078_RS12000 yqeK 2380223..2380807 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  OS078_RS12005 nadD 2380797..2381366 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  OS078_RS12010 yhbY 2381369..2381659 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  OS078_RS12015 aroE 2381663..2382469 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  OS078_RS12020 yqeH 2382483..2383583 (-) 1101 WP_001280148.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=759074 OS078_RS11985 WP_001792568.1 2378424..2379110(-) (comEA) [Staphylococcus aureus strain Zed]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=759074 OS078_RS11985 WP_001792568.1 2378424..2379110(-) (comEA) [Staphylococcus aureus strain Zed]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969