Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   OS092_RS06655 Genome accession   NZ_CP113009
Coordinates   1336214..1336900 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain Orianna     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1331214..1341900
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS092_RS06635 rpsT 1332128..1332379 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  OS092_RS06640 holA 1332424..1333398 (-) 975 WP_001282562.1 DNA polymerase III subunit delta -
  OS092_RS06645 comEC 1333455..1335656 (-) 2202 WP_001807336.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  OS092_RS06650 - 1335661..1336122 (-) 462 WP_000439693.1 ComE operon protein 2 -
  OS092_RS06655 comEA 1336214..1336900 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  OS092_RS06660 - 1336940..1337656 (-) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  OS092_RS06665 rsfS 1337659..1338012 (-) 354 WP_001088022.1 ribosome silencing factor -
  OS092_RS06670 yqeK 1338013..1338597 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  OS092_RS06675 nadD 1338587..1339156 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  OS092_RS06680 yhbY 1339159..1339449 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  OS092_RS06685 aroE 1339453..1340259 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  OS092_RS06690 yqeH 1340273..1341373 (-) 1101 WP_001280148.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=759022 OS092_RS06655 WP_001792568.1 1336214..1336900(-) (comEA) [Staphylococcus aureus strain Orianna]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=759022 OS092_RS06655 WP_001792568.1 1336214..1336900(-) (comEA) [Staphylococcus aureus strain Orianna]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969