Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   OH540_RS16530 Genome accession   NZ_CP124542
Coordinates   3704514..3705638 (+) Length   374 a.a.
NCBI ID   WP_064729139.1    Uniprot ID   A0A191V189
Organism   Streptomyces sp. BPPL-273     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3699514..3710638
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OH540_RS16515 (OH540_16515) - 3699914..3700726 (+) 813 WP_161341941.1 hypothetical protein -
  OH540_RS16520 (OH540_16520) - 3700773..3702536 (-) 1764 WP_283014400.1 hypothetical protein -
  OH540_RS16525 (OH540_16525) radA 3703023..3704432 (+) 1410 WP_064729140.1 DNA repair protein RadA Machinery gene
  OH540_RS16530 (OH540_16530) disA 3704514..3705638 (+) 1125 WP_064729139.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  OH540_RS16535 (OH540_16535) - 3705663..3706514 (-) 852 WP_283014401.1 hypothetical protein -
  OH540_RS16540 (OH540_16540) - 3706689..3707333 (+) 645 WP_226487422.1 phosphatase PAP2 family protein -
  OH540_RS16545 (OH540_16545) - 3707338..3708003 (-) 666 WP_226487421.1 response regulator transcription factor -
  OH540_RS16550 (OH540_16550) - 3708000..3709691 (-) 1692 WP_283014402.1 sensor histidine kinase -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40071.88 Da        Isoelectric Point: 5.0058

>NTDB_id=758476 OH540_RS16530 WP_064729139.1 3704514..3705638(+) (disA) [Streptomyces sp. BPPL-273]
MAANDRAAAPGKSGGSAGADGLMRASLSAVAPGTLLRDGLERVLRGNTGGLMVLGSDKTVEAMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLLPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDKLSHAELLELSTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=758476 OH540_RS16530 WP_064729139.1 3704514..3705638(+) (disA) [Streptomyces sp. BPPL-273]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTGCCGATGGCCTGATGCGCGCCTCGCT
GAGCGCCGTGGCGCCCGGCACCCTGCTGCGGGACGGCCTGGAACGGGTCCTTCGCGGCAACACCGGCGGTCTCATGGTGC
TGGGGTCGGACAAGACCGTCGAGGCGATGTGCACGGGCGGCTTCGTGCTGGACGTCGAGTTCACGGCGACCCGCCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTCTCCTCGGACCTGTCGAAGATCCTGCGGGCGGGTGTGCAGCTGCTGCC
CGACCCGACCATTCCGACCGAGGAGACCGGCACCCGGCACCGTACGGCGGACCGGGTCAGCAAGCAGGTCGGCTTCCCCG
TCGTGTCCGTTTCGCAGTCCATGCGGCTCATCGCCCTCTATGTCGACGGGCAGCGGCGGGTGCTGGAGGACTCCGCGGCG
ATCCTGTCCCGGGCCAACCAGGCGCTGGCCACCCTGGAGCGCTACAAGCTCCGGCTCGACGAGGTCGCCGGCACGCTCTC
CGCGCTGGAGATCGAGGACCTGGTGACCGTCCGGGACGTGTCGGCGGTCGCGCAGCGGCTGGAGATGGTGCGCCGGATCG
CCACCGAGATCGCCGAGTACGTGGTCGAGCTGGGGACGGACGGGCGGCTGCTCGCGCTCCAGCTGGACGAGCTGATCGCC
GGCGTGGAGCCCGAACGCGAGCTGGTCGTGCGGGACTACGTGCCCGAGCCGACCGCCAAGCGGTCCCGTACGGTCGACGA
GGCGCTCGCCGAGCTGGACAAGCTCAGCCACGCCGAGCTGCTCGAACTGTCCACGGTGGCCCGGGCGCTGGGTTACACCG
GGTCCCCCGAGACGCTGGACTCGGCGGTGTCGCCGCGCGGCTTCCGGCTGCTGGCGAAGGTGCCGCGGCTGCCGGGCGCC
ATCATCGACCGCCTCGTGGAGCACTTCGGCGGGCTGCAGAAGCTGCTCGCCGCCAGTGTCGACGACCTCCAGACGGTCGA
CGGCGTCGGCGAGGCGCGGGCCCGCAGCGTGCGCGAGGGGCTGTCGCGGCTCGCGGAGTCGTCGATCCTGGAGCGGTACG
TCTGA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A191V189

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.983

96.524

0.444