Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QJP86_RS10425 Genome accession   NZ_CP124513
Coordinates   2187346..2188002 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain AVS0366     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2182346..2193002
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QJP86_RS10395 (QJP86_10395) dcyD 2183225..2184211 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  QJP86_RS10400 (QJP86_10400) tcyL 2184226..2184894 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QJP86_RS10405 (QJP86_10405) tcyN 2184891..2185643 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QJP86_RS10410 (QJP86_10410) sdiA 2185873..2186595 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  QJP86_RS10415 (QJP86_10415) yecF 2186663..2186887 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QJP86_RS10420 (QJP86_10420) yecU 2186874..2187050 (-) 177 WP_001307856.1 protein YecU -
  QJP86_RS10425 (QJP86_10425) letA 2187346..2188002 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QJP86_RS10430 (QJP86_10430) uvrC 2187999..2189831 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QJP86_RS10435 (QJP86_10435) pgsA 2189888..2190436 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QJP86_RS10455 (QJP86_10455) yecA 2191085..2191750 (+) 666 WP_000847877.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=758222 QJP86_RS10425 WP_000611328.1 2187346..2188002(+) (letA) [Escherichia coli strain AVS0366]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=758222 QJP86_RS10425 WP_000611328.1 2187346..2188002(+) (letA) [Escherichia coli strain AVS0366]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482