Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QJP74_RS13405 Genome accession   NZ_CP124429
Coordinates   2689416..2690072 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain AVS0051     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2684416..2695072
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QJP74_RS13370 (QJP74_13370) - 2685195..2685413 (+) 219 WP_283192231.1 DUF4224 domain-containing protein -
  QJP74_RS13375 (QJP74_13375) - 2685382..2686398 (+) 1017 WP_001531780.1 tyrosine-type recombinase/integrase -
  QJP74_RS13395 (QJP74_13395) pgsA 2686982..2687530 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QJP74_RS13400 (QJP74_13400) uvrC 2687587..2689419 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QJP74_RS13405 (QJP74_13405) letA 2689416..2690072 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QJP74_RS13410 (QJP74_13410) yecU 2690368..2690544 (+) 177 WP_001307856.1 protein YecU -
  QJP74_RS13415 (QJP74_13415) yecF 2690531..2690755 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  QJP74_RS13420 (QJP74_13420) sdiA 2690823..2691545 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  QJP74_RS13425 (QJP74_13425) tcyN 2691775..2692527 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QJP74_RS13430 (QJP74_13430) tcyL 2692524..2693192 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  QJP74_RS13435 (QJP74_13435) dcyD 2693207..2694193 (-) 987 WP_001128232.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=756488 QJP74_RS13405 WP_000611328.1 2689416..2690072(-) (letA) [Escherichia coli strain AVS0051]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=756488 QJP74_RS13405 WP_000611328.1 2689416..2690072(-) (letA) [Escherichia coli strain AVS0051]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482