Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OP858_RS04570 Genome accession   NZ_CP110784
Coordinates   946966..947595 (+) Length   209 a.a.
NCBI ID   WP_002453599.1    Uniprot ID   -
Organism   Staphylococcus capitis strain CCSM0123     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 941966..952595
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OP858_RS04540 (OP858_04540) isaB 942143..942685 (+) 543 WP_002453604.1 immunodominant staphylococcal antigen IsaB family protein -
  OP858_RS04545 (OP858_04545) - 942768..943757 (-) 990 WP_186334631.1 FUSC family protein -
  OP858_RS04550 (OP858_04550) map 943931..944686 (+) 756 WP_002453602.1 type I methionyl aminopeptidase -
  OP858_RS04555 (OP858_04555) - 944831..945217 (+) 387 WP_002453601.1 hypothetical protein -
  OP858_RS04560 (OP858_04560) liaF 945232..945933 (+) 702 WP_002453600.1 cell wall-active antibiotics response protein LiaF -
  OP858_RS04565 (OP858_04565) vraS 945930..946976 (+) 1047 WP_002435929.1 sensor histidine kinase Regulator
  OP858_RS04570 (OP858_04570) vraR 946966..947595 (+) 630 WP_002453599.1 two-component system response regulator VraR Regulator
  OP858_RS04575 (OP858_04575) - 947661..948914 (-) 1254 WP_016898704.1 YihY/virulence factor BrkB family protein -
  OP858_RS04580 (OP858_04580) - 949251..949535 (-) 285 WP_002435890.1 hypothetical protein -
  OP858_RS04585 (OP858_04585) - 949542..950006 (-) 465 WP_267263565.1 low molecular weight protein-tyrosine-phosphatase -
  OP858_RS04590 (OP858_04590) - 950147..950353 (+) 207 WP_002435959.1 DUF1128 domain-containing protein -
  OP858_RS04595 (OP858_04595) - 950367..951608 (+) 1242 WP_002453597.1 aminopeptidase -
  OP858_RS04600 (OP858_04600) - 951710..952240 (+) 531 WP_002453596.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23597.20 Da        Isoelectric Point: 4.8053

>NTDB_id=756089 OP858_RS04570 WP_002453599.1 946966..947595(+) (vraR) [Staphylococcus capitis strain CCSM0123]
MAIKVLFVDDHEMVRIGISSYLSTQQDIEVVGEGASGKEAIEKAHELKPDLILMDLLMDDMDGVEATTEIKKDLPHIRVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIADAVRKTDQGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=756089 OP858_RS04570 WP_002453599.1 946966..947595(+) (vraR) [Staphylococcus capitis strain CCSM0123]
ATGGCGATTAAAGTATTGTTTGTTGATGACCATGAAATGGTTAGAATTGGTATTTCAAGCTATCTATCTACACAACAGGA
TATTGAAGTAGTTGGAGAAGGTGCTTCAGGTAAAGAAGCTATCGAAAAAGCCCATGAGTTGAAACCAGATTTAATTTTAA
TGGATTTACTTATGGATGATATGGATGGTGTAGAAGCTACTACTGAAATTAAAAAGGATTTACCTCACATAAGAGTAGTA
ATGTTAACAAGCTTTATCGAGGATAAAGAAGTTTATCGAGCATTAGATGCTGGGGTAGATAGTTATATCTTAAAAACGAC
TAGCGCGAGTGACATTGCTGACGCGGTACGTAAAACAGATCAAGGGGAATCTGTTTTTGAACCAGAAGTACTTGTAAAAA
TGAGAAACCGCATGAAAAAACGTGCTGAGTTATATGAAATGCTTACAGAGCGTGAAATGGAAATTTTATTATTAATTGCC
AAAGGTTACTCTAACCAAGAAATTGCTAGCGCCTCTCATATCACTATTAAAACTGTTAAAACACACGTAAGTAATATATT
GAGTAAGTTAGAAGTTCAAGATAGAACTCAAGCTGTTATTTATGCTTTCCAACATAATTTGATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.737

100

0.947
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.364