Detailed information NTG0754161

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: PALA24_RS10130
• Genome accession: NZ_CP110344
• Coordinates: 2171800..2174025 (+)
• Length: 741 a.a.
• NCBI ID: WP_003119806.1
• Uniprot ID: A0A1S1C5Z8
• Organism: Pseudomonas aeruginosa strain PALA24
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2166800..2179025

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PALA24_RS10105 (PALA24_02012)	-	2167106..2167705 (-)	600	WP_003105196.1	PilZ domain-containing protein	-
PALA24_RS10110 (PALA24_02013)	-	2167808..2169058 (+)	1251	WP_003091170.1	lipoprotein-releasing ABC transporter permease subunit	-
PALA24_RS10115 (PALA24_02014)	lolD	2169051..2169734 (+)	684	WP_003091168.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
PALA24_RS10120 (PALA24_02015)	-	2169804..2171048 (+)	1245	WP_003113987.1	lipoprotein-releasing ABC transporter permease subunit	-
PALA24_RS10125 (PALA24_02016)	-	2171136..2171669 (-)	534	WP_003091165.1	DUF2062 domain-containing protein	-
PALA24_RS10130 (PALA24_02017)	comA	2171800..2174025 (+)	2226	WP_003119806.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
PALA24_RS10135 (PALA24_02018)	exbB	2174098..2174733 (+)	636	WP_003091163.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
PALA24_RS10140 (PALA24_02019)	-	2174730..2175170 (+)	441	WP_003091161.1	ExbD/TolR family protein	-
PALA24_RS10145 (PALA24_02020)	lpxK	2175170..2176168 (+)	999	WP_003091159.1	tetraacyldisaccharide 4'-kinase	-
PALA24_RS10150 (PALA24_02021)	-	2176206..2176391 (+)	186	WP_003091157.1	Trm112 family protein	-
PALA24_RS10155 (PALA24_02022)	kdsB	2176391..2177155 (+)	765	WP_003091155.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
PALA24_RS10160 (PALA24_02023)	-	2177155..2177619 (+)	465	WP_003091154.1	low molecular weight protein-tyrosine-phosphatase	-
PALA24_RS10165 (PALA24_02024)	murB	2177616..2178635 (+)	1020	WP_003091153.1	UDP-N-acetylmuramate dehydrogenase	-

Sequence

Protein

• Length: 741 a.a.
• Molecular weight: 80048.70 Da
• Isoelectric Point: 10.5155

>NTDB_id=754161 PALA24_RS10130 WP_003119806.1 2171800..2174025(+) (comA) [Pseudomonas aeruginosa strain PALA24]
MRLGLPALAAGLLALRFLAELPSVGWLLGMAAAGLLLLFGRLYWLGLFLLGFAWACGSAQVALDGRLAAELDGRTLWLEG
RVVDLPASGEGVTRFRLEEVRAARGVLLPERLRLSWRGAPPLMGGERWRLAVTLKRPRGLVNAAGFDYEAWLLAQRVGAV
GTVKAGQRLQPASGLDAWRDAWRQRLLAVDAQGRGAALAALVLGDGSGLSAAEWRMFQDTGTVHLMVISGSHISLLAGML
YGLVAALHRLGCWPRRLPWLPCACALGLLGAWSYGLMAGFEVPVRRACLMVSLALVWRLRFRHLGLLTPLLATLVLVLLV
EPLASLQAGFWLSFLAVALLLWLFAGRLGRWRWWAAWGRAQWGMALGLAMPLLALGLPLSLSGAPANLLAVPWIELLVVP
PALAGSLLLWVPGLGEGLLRAAGVSLDLLFRALGLLAGLAEAWQPPAAAAWSVALGMLGALCWLAPAGLPLRALGAALLL
PALLPSSPPVEWGRAEVRVLDVGQGLAVLVRTREHVLLYDSGARQGAFDMGERVVVPVLRSLDLRRLDGLLLSHADNDHA
GGAPTVASRFPPVWLVSGEPARLPSPLFADSCDERSWSWDGVVFEQWAWAQAGDSNDRSCVLRVEADGEVLLLTGDISRA
AEHAWLARQADPRVDWLLAPHHGSRSSSGVAFVLRTRPRHVLVSRGWRNAFGHPHGEVMERYARVAAQVHDTARDGALTF
LLGSRGGARRERDSAHFWREK

Nucleotide

• Length: 2226 bp

>NTDB_id=754161 PALA24_RS10130 WP_003119806.1 2171800..2174025(+) (comA) [Pseudomonas aeruginosa strain PALA24]
ATGCGCCTGGGATTGCCAGCCCTCGCCGCGGGGCTGCTGGCCCTGCGCTTCCTGGCGGAATTGCCGTCGGTCGGCTGGCT
GCTGGGCATGGCCGCCGCCGGACTGTTGCTGCTGTTCGGCCGGCTGTACTGGCTGGGGTTGTTCCTGCTCGGGTTCGCCT
GGGCCTGCGGCTCGGCGCAAGTCGCCCTGGACGGACGCCTGGCCGCCGAGCTGGATGGTCGCACCCTTTGGCTGGAGGGG
CGTGTGGTCGATCTGCCGGCGAGCGGCGAGGGCGTCACGCGCTTCCGGCTGGAGGAGGTCCGCGCTGCGCGGGGCGTGCT
TCTTCCCGAGCGTCTGCGCCTGAGCTGGCGCGGCGCGCCGCCGCTGATGGGCGGCGAACGCTGGCGCCTGGCGGTGACCC
TGAAACGCCCCCGCGGCCTGGTGAACGCGGCGGGTTTCGACTACGAGGCCTGGTTGTTGGCGCAGCGGGTCGGTGCTGTG
GGCACGGTGAAGGCGGGCCAGCGCCTGCAGCCGGCCAGCGGCCTGGATGCCTGGCGCGATGCCTGGCGCCAGCGCCTGCT
GGCGGTCGACGCACAGGGGCGCGGCGCCGCCCTGGCGGCGCTGGTGCTGGGGGATGGCTCGGGGTTGAGCGCGGCCGAGT
GGCGCATGTTCCAGGACACCGGCACCGTGCATCTGATGGTCATCTCCGGTTCGCATATCTCGTTGCTGGCGGGGATGCTC
TATGGCCTGGTGGCGGCCTTGCATCGCCTGGGCTGCTGGCCGCGGCGCCTGCCCTGGCTGCCCTGTGCCTGCGCCCTGGG
TTTGCTTGGTGCCTGGAGCTACGGGTTGATGGCGGGTTTCGAGGTCCCGGTGCGGCGCGCCTGCCTGATGGTCAGCCTGG
CGCTGGTCTGGCGCCTGCGTTTCCGCCACCTGGGCTTGCTGACCCCGCTGCTGGCAACGCTGGTGCTGGTCTTGCTGGTC
GAGCCGCTGGCCAGCCTGCAGGCGGGGTTCTGGCTGTCGTTCCTGGCGGTTGCCCTGCTGCTCTGGCTGTTCGCCGGGCG
CCTTGGGCGCTGGCGCTGGTGGGCGGCCTGGGGGCGGGCGCAGTGGGGGATGGCGCTGGGGCTGGCGATGCCGCTGCTGG
CGCTGGGCCTGCCGTTGAGCCTGAGCGGAGCGCCGGCCAACCTGCTGGCGGTGCCTTGGATCGAACTGCTGGTAGTGCCC
CCGGCCCTGGCGGGGAGCCTGCTGCTGTGGGTGCCCGGGCTGGGCGAGGGGCTGCTTCGCGCCGCTGGCGTTTCGCTGGA
CCTGCTGTTTCGTGCGCTTGGCCTGCTGGCGGGCCTGGCCGAGGCCTGGCAGCCACCCGCCGCAGCGGCCTGGAGCGTAG
CGCTGGGCATGCTCGGCGCGCTCTGCTGGCTGGCGCCGGCTGGCTTGCCGTTGCGTGCCCTCGGTGCCGCGTTGCTACTG
CCGGCATTGTTGCCGTCATCGCCGCCTGTCGAATGGGGGCGGGCGGAAGTGCGGGTGCTGGACGTCGGCCAGGGGCTGGC
CGTGCTGGTGCGTACCCGAGAGCATGTCTTGCTCTATGACAGCGGTGCGCGGCAGGGGGCGTTCGACATGGGCGAGCGGG
TGGTGGTGCCGGTGCTGCGCAGCCTGGACCTGCGGCGCCTGGACGGCCTGTTGCTGAGCCATGCCGACAACGACCATGCA
GGCGGTGCTCCTACGGTCGCTTCCCGATTCCCGCCGGTTTGGCTGGTCAGCGGCGAACCCGCGCGCCTGCCTTCGCCGTT
GTTCGCGGACAGCTGCGACGAGCGGAGCTGGTCCTGGGATGGCGTGGTTTTCGAACAGTGGGCATGGGCACAGGCCGGCG
ACAGCAACGACCGCTCCTGTGTGCTGAGGGTCGAGGCCGATGGCGAAGTCCTGCTGCTGACCGGGGACATCTCGCGTGCG
GCCGAGCATGCCTGGCTGGCGCGACAGGCCGATCCCCGGGTCGACTGGTTGCTGGCGCCGCATCATGGCAGCCGCAGTTC
CTCCGGAGTCGCCTTCGTGTTGCGTACGCGGCCTCGCCATGTGCTGGTCTCGCGAGGTTGGCGCAACGCCTTCGGCCATC
CCCATGGCGAAGTGATGGAGCGTTACGCGAGGGTCGCCGCGCAGGTCCACGACACGGCACGCGACGGTGCCCTGACGTTT
CTCCTCGGAAGCCGTGGCGGCGCACGCCGGGAGCGTGATTCGGCGCACTTCTGGCGGGAAAAATGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (21-168)

• Metallo-beta-lactamase superfamily (Lactamase_B) (501-666)

• Competence protein (Competence) (201-464)

3D structure

• AlphaFold DB: A0A1S1C5Z8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	58.807	97.301	0.572
comA	Ralstonia pseudosolanacearum GMI1000	35.48	100	0.364