Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QJP81_RS14925 Genome accession   NZ_CP124320
Coordinates   3018705..3019361 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain AVS0754     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3013705..3024361
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QJP81_RS14895 (QJP81_14895) yecA 3014957..3015622 (-) 666 WP_000847877.1 UPF0149 family protein YecA -
  QJP81_RS14915 (QJP81_14915) pgsA 3016271..3016819 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QJP81_RS14920 (QJP81_14920) uvrC 3016876..3018708 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QJP81_RS14925 (QJP81_14925) letA 3018705..3019361 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QJP81_RS14930 (QJP81_14930) yecU 3019657..3019833 (+) 177 WP_001307856.1 protein YecU -
  QJP81_RS14935 (QJP81_14935) yecF 3019820..3020044 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  QJP81_RS14940 (QJP81_14940) sdiA 3020112..3020834 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  QJP81_RS14945 (QJP81_14945) tcyN 3021064..3021816 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QJP81_RS14950 (QJP81_14950) tcyL 3021813..3022481 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  QJP81_RS14955 (QJP81_14955) dcyD 3022496..3023482 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=753739 QJP81_RS14925 WP_000611328.1 3018705..3019361(-) (letA) [Escherichia coli strain AVS0754]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=753739 QJP81_RS14925 WP_000611328.1 3018705..3019361(-) (letA) [Escherichia coli strain AVS0754]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482