Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QC817_RS09215 Genome accession   NZ_CP123963
Coordinates   1897348..1898004 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain L6-21     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1892348..1903004
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QC817_RS09185 (QC817_09185) dcyD 1893228..1894214 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  QC817_RS09190 (QC817_09190) tcyL 1894229..1894897 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QC817_RS09195 (QC817_09195) tcyN 1894894..1895646 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QC817_RS09200 (QC817_09200) sdiA 1895876..1896598 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  QC817_RS09205 (QC817_09205) yecF 1896665..1896889 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QC817_RS09210 (QC817_09210) yecU 1896876..1897052 (-) 177 WP_001307856.1 protein YecU -
  QC817_RS23770 - 1897135..1897206 (-) 72 Protein_1796 transcriptional regulator -
  QC817_RS09215 (QC817_09215) letA 1897348..1898004 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QC817_RS09220 (QC817_09220) uvrC 1898001..1899833 (+) 1833 WP_281103672.1 excinuclease ABC subunit UvrC Machinery gene
  QC817_RS09225 (QC817_09225) pgsA 1899890..1900438 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QC817_RS09245 (QC817_09245) - 1901134..1901874 (-) 741 WP_105629615.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=753324 QC817_RS09215 WP_000611328.1 1897348..1898004(+) (letA) [Escherichia coli strain L6-21]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=753324 QC817_RS09215 WP_000611328.1 1897348..1898004(+) (letA) [Escherichia coli strain L6-21]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482