Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   QHG49_RS15815 Genome accession   NZ_CP123923
Coordinates   3646808..3647932 (+) Length   374 a.a.
NCBI ID   WP_037660305.1    Uniprot ID   A0A1X4GT45
Organism   Streptomyces sp. WP-1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3641808..3652932
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QHG49_RS15805 (QHG49_15810) - 3643278..3645119 (-) 1842 WP_370530468.1 hypothetical protein -
  QHG49_RS15810 (QHG49_15815) radA/sms 3645318..3646727 (+) 1410 WP_145487922.1 DNA repair protein RadA Machinery gene
  QHG49_RS15815 (QHG49_15820) disA 3646808..3647932 (+) 1125 WP_037660305.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  QHG49_RS15820 (QHG49_15825) - 3647960..3648790 (-) 831 WP_301490089.1 hypothetical protein -
  QHG49_RS15825 (QHG49_15830) - 3648970..3649845 (+) 876 WP_145487924.1 A/G-specific adenine glycosylase -
  QHG49_RS15830 (QHG49_15835) - 3650127..3650666 (+) 540 WP_037660309.1 SigE family RNA polymerase sigma factor -
  QHG49_RS15835 (QHG49_15840) - 3650708..3651319 (+) 612 WP_159708427.1 hypothetical protein -
  QHG49_RS15840 (QHG49_15845) cseB 3651371..3652075 (+) 705 WP_159703736.1 two-component system response regulator CseB -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 39932.68 Da        Isoelectric Point: 4.9187

>NTDB_id=753066 QHG49_RS15815 WP_037660305.1 3646808..3647932(+) (disA) [Streptomyces sp. WP-1]
MAANDRAAAPGKSGGSAGSDGLMRAALSAVAPGTAMRDGLERILRGNTGGLIVLGSDKTVEAMCTGGFVLDVEFAATRLR
ELCKLDGGIVLSSDLSKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLEELIA
GVEPDRELVVRDYVPEPTAKRSRTVEEALSELNALTQAELIEVGTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=753066 QHG49_RS15815 WP_037660305.1 3646808..3647932(+) (disA) [Streptomyces sp. WP-1]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTTCCGATGGCCTGATGCGCGCTGCCCT
GAGCGCCGTGGCACCCGGTACGGCCATGCGGGACGGCCTGGAGCGCATCCTGCGCGGCAACACCGGCGGCCTGATCGTGC
TCGGCTCCGACAAGACCGTCGAGGCGATGTGCACCGGCGGCTTCGTGCTGGACGTGGAGTTCGCCGCGACCCGGCTGCGG
GAGCTGTGCAAGCTGGACGGCGGCATCGTGCTGTCCTCGGACCTCTCGAAGATCCTGCGCGCGGGCGTCCAGCTGGTCCC
GGACCCGACCATCCCCACCGAGGAGACGGGCACCCGGCACCGGACGGCGGACCGGGTGAGCAAGCAGGTCGGCTTCCCCG
TCGTCTCCGTGTCCCAGTCGATGCGGCTGATCGCGCTCTACGTCGACGGTCAGCGCCGCGTCCTGGAGGACTCGGCGGCG
ATCCTCTCCCGCGCGAACCAGGCGCTGGCCACGCTGGAGCGGTACAAGCTCCGCCTGGACGAGGTGGCGGGCACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTGACGGTGCGGGACGTGTCCGCCGTCGCACAGCGTCTGGAGATGGTGCGCCGGATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTGGGCACCGACGGCCGGCTGCTCGCGCTCCAGCTGGAGGAGCTGATCGCG
GGGGTCGAGCCGGACCGGGAGCTGGTCGTACGGGACTATGTGCCCGAGCCGACCGCGAAGCGCTCCCGCACGGTGGAGGA
GGCCCTGTCCGAGCTGAACGCGCTCACCCAGGCCGAGCTGATCGAGGTCGGCACGGTGGCGCGGGCGCTGGGCTACACCG
GGTCGCCCGAGACCCTGGACTCCGCGGTGTCCCCGCGGGGCTTCCGGCTGCTGGCCAAGGTGCCGCGGCTGCCGGGGGCG
ATCATCGACCGGCTGGTGGAGCACTTCGGCGGGCTGCAGAAGCTGTTGGCCGCGAGTGTGGACGATCTGCAGACGGTGGA
CGGTGTGGGCGAGGCGCGGGCGAGGAGCGTGCGGGAGGGACTCTCGCGGCTGGCCGAGTCCTCGATCCTGGAGCGGTACG
TCTGA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X4GT45

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.143

93.583

0.422