Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   NOV96_RS08340 Genome accession   NZ_CP110141
Coordinates   1694605..1695294 (-) Length   229 a.a.
NCBI ID   WP_002942700.1    Uniprot ID   A0A126UNE5
Organism   Streptococcus suis strain WUSS030     
Function   repress comR expression (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1687238..1694495 1694605..1695294 flank 110


Gene organization within MGE regions


Location: 1687238..1695294
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NOV96_RS08310 (NOV96_08310) - 1687238..1688527 (+) 1290 WP_014636745.1 IS4-like element ISSsu2 family transposase -
  NOV96_RS08315 (NOV96_08315) - 1688687..1689751 (-) 1065 WP_014636829.1 LLM class flavin-dependent oxidoreductase -
  NOV96_RS08320 (NOV96_08320) - 1689877..1691124 (-) 1248 WP_004194760.1 ABC transporter permease -
  NOV96_RS08325 (NOV96_08325) - 1691125..1691820 (-) 696 WP_004194759.1 ABC transporter ATP-binding protein -
  NOV96_RS08330 (NOV96_08330) - 1691801..1692958 (-) 1158 WP_004194758.1 efflux RND transporter periplasmic adaptor subunit -
  NOV96_RS08335 (NOV96_08335) - 1693206..1694495 (-) 1290 WP_002935134.1 IS4-like element ISSsu2 family transposase -
  NOV96_RS08340 (NOV96_08340) covR 1694605..1695294 (-) 690 WP_002942700.1 DNA-binding response regulator Regulator

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26225.11 Da        Isoelectric Point: 5.3968

>NTDB_id=752666 NOV96_RS08340 WP_002942700.1 1694605..1695294(-) (covR) [Streptococcus suis strain WUSS030]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELAAELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=752666 NOV96_RS08340 WP_002942700.1 1694605..1695294(-) (covR) [Streptococcus suis strain WUSS030]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTGCAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A126UNE5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432