Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QFB78_RS09470 Genome accession   NZ_CP123593
Coordinates   1968977..1969633 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain DJH_183sputum     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1963977..1974633
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QFB78_RS09440 dcyD 1964856..1965842 (+) 987 WP_001128218.1 D-cysteine desulfhydrase -
  QFB78_RS09445 tcyL 1965857..1966525 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QFB78_RS09450 tcyN 1966522..1967274 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QFB78_RS09455 sdiA 1967504..1968226 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  QFB78_RS09460 yecF 1968294..1968518 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QFB78_RS09465 yecU 1968505..1968681 (-) 177 WP_000590347.1 protein YecU -
  QFB78_RS23825 - 1968764..1968835 (-) 72 Protein_1851 transcriptional regulator -
  QFB78_RS09470 letA 1968977..1969633 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QFB78_RS09475 uvrC 1969630..1971462 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QFB78_RS09480 pgsA 1971519..1972067 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QFB78_RS09500 yecA 1972717..1973382 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=751307 QFB78_RS09470 WP_000611335.1 1968977..1969633(+) (letA) [Escherichia coli strain DJH_183sputum]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=751307 QFB78_RS09470 WP_000611335.1 1968977..1969633(+) (letA) [Escherichia coli strain DJH_183sputum]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486