Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   OHM48_RS08175 Genome accession   NZ_CP109942
Coordinates   1638465..1639154 (-) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain ID35541     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1633465..1644154
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHM48_RS08150 (OHM48_08150) - 1633935..1634648 (-) 714 WP_024399628.1 NADPH-dependent oxidoreductase -
  OHM48_RS08155 (OHM48_08155) dnaI 1634645..1635544 (-) 900 WP_014636109.1 primosomal protein DnaI -
  OHM48_RS08160 (OHM48_08160) - 1635544..1636695 (-) 1152 WP_105115229.1 replication initiation/membrane attachment protein -
  OHM48_RS08165 (OHM48_08165) nrdR 1636682..1637173 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  OHM48_RS08170 (OHM48_08170) - 1637245..1638375 (-) 1131 WP_012027644.1 AI-2E family transporter -
  OHM48_RS08175 (OHM48_08175) covR 1638465..1639154 (-) 690 WP_012027645.1 DNA-binding response regulator Regulator
  OHM48_RS08180 (OHM48_08180) gndA 1639236..1640663 (-) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  OHM48_RS08185 (OHM48_08185) - 1640760..1641299 (-) 540 WP_105115228.1 DUF177 domain-containing protein -
  OHM48_RS08190 (OHM48_08190) trxB 1641309..1642226 (-) 918 WP_029751717.1 thioredoxin-disulfide reductase -
  OHM48_RS08195 (OHM48_08195) - 1642240..1642464 (-) 225 WP_002936682.1 DUF4059 family protein -
  OHM48_RS08200 (OHM48_08200) - 1642482..1643825 (-) 1344 WP_202054744.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=751105 OHM48_RS08175 WP_012027645.1 1638465..1639154(-) (covR) [Streptococcus suis strain ID35541]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=751105 OHM48_RS08175 WP_012027645.1 1638465..1639154(-) (covR) [Streptococcus suis strain ID35541]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTGTTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGACTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTGTATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATTAAAACGGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432