Detailed information
Bioinformatically predicted
Overview
| Name | clpX | Type | Regulator |
| Locus tag | OHM52_RS04670 | Genome accession | NZ_CP109937 |
| Coordinates | 932369..933595 (+) | Length | 408 a.a. |
| NCBI ID | WP_002934974.1 | Uniprot ID | G7SE29 |
| Organism | Streptococcus suis strain TRG6 | ||
| Function | require for competence development (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 909534..984080 | 932369..933595 | within | 0 |
Gene organization within MGE regions
Location: 909534..984080
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OHM52_RS04570 (OHM52_04570) | pfkA | 909635..910645 (+) | 1011 | WP_024395108.1 | 6-phosphofructokinase | - |
| OHM52_RS04575 (OHM52_04575) | pyk | 910711..912216 (+) | 1506 | WP_024385559.1 | pyruvate kinase | - |
| OHM52_RS04580 (OHM52_04580) | ide-Ssuis | 912378..915560 (+) | 3183 | WP_264516790.1 | host-specific IgM cysteine endopeptidase Ide-Ssuis | - |
| OHM52_RS04585 (OHM52_04585) | - | 915885..916994 (-) | 1110 | WP_024395110.1 | FAD-binding oxidoreductase | - |
| OHM52_RS04590 (OHM52_04590) | - | 917079..917696 (+) | 618 | WP_011922094.1 | GDSL-type esterase/lipase family protein | - |
| OHM52_RS04595 (OHM52_04595) | lepB | 917739..918281 (+) | 543 | WP_014736040.1 | signal peptidase I | - |
| OHM52_RS04600 (OHM52_04600) | - | 918330..919586 (-) | 1257 | WP_248041904.1 | ISL3 family transposase | - |
| OHM52_RS04605 (OHM52_04605) | glmS | 919893..921704 (+) | 1812 | WP_024381447.1 | glutamine--fructose-6-phosphate transaminase (isomerizing) | - |
| OHM52_RS04610 (OHM52_04610) | - | 922047..923210 (-) | 1164 | Protein_876 | IS30 family transposase | - |
| OHM52_RS04615 (OHM52_04615) | - | 923410..923784 (+) | 375 | WP_043032857.1 | DUF1149 family protein | - |
| OHM52_RS04620 (OHM52_04620) | - | 923786..924637 (+) | 852 | WP_024394325.1 | DegV family protein | - |
| OHM52_RS04625 (OHM52_04625) | dapB | 924646..925413 (+) | 768 | WP_024394324.1 | 4-hydroxy-tetrahydrodipicolinate reductase | - |
| OHM52_RS04630 (OHM52_04630) | - | 925410..926621 (+) | 1212 | WP_024394323.1 | CCA tRNA nucleotidyltransferase | - |
| OHM52_RS04635 (OHM52_04635) | - | 926614..928482 (+) | 1869 | WP_024394322.1 | ABC-F family ATP-binding cassette domain-containing protein | - |
| OHM52_RS04640 (OHM52_04640) | - | 928483..928818 (+) | 336 | WP_024394321.1 | hypothetical protein | - |
| OHM52_RS04645 (OHM52_04645) | - | 928914..929873 (+) | 960 | WP_024394320.1 | ROK family glucokinase | - |
| OHM52_RS04650 (OHM52_04650) | - | 929999..930277 (+) | 279 | WP_024394319.1 | hypothetical protein | - |
| OHM52_RS04655 (OHM52_04655) | - | 930289..930591 (+) | 303 | WP_024394318.1 | hypothetical protein | - |
| OHM52_RS04660 (OHM52_04660) | - | 930644..931483 (+) | 840 | WP_024394317.1 | thymidylate synthase | - |
| OHM52_RS04665 (OHM52_04665) | - | 931659..932171 (+) | 513 | WP_192062960.1 | dihydrofolate reductase | - |
| OHM52_RS04670 (OHM52_04670) | clpX | 932369..933595 (+) | 1227 | WP_002934974.1 | ATP-dependent Clp protease ATP-binding subunit ClpX | Regulator |
| OHM52_RS04675 (OHM52_04675) | yihA | 933651..934238 (+) | 588 | WP_014638915.1 | ribosome biogenesis GTP-binding protein YihA/YsxC | - |
| OHM52_RS04680 (OHM52_04680) | ndk | 934261..934674 (+) | 414 | WP_024394314.1 | nucleoside-diphosphate kinase | - |
| OHM52_RS04685 (OHM52_04685) | lepA | 934770..936602 (+) | 1833 | WP_002943192.1 | translation elongation factor 4 | - |
| OHM52_RS04690 (OHM52_04690) | - | 936652..936834 (-) | 183 | WP_002934978.1 | 4-oxalocrotonate tautomerase | - |
| OHM52_RS04695 (OHM52_04695) | - | 936969..938276 (+) | 1308 | WP_002934980.1 | excalibur calcium-binding domain-containing protein | - |
| OHM52_RS04700 (OHM52_04700) | - | 938338..938562 (+) | 225 | WP_002934981.1 | hypothetical protein | - |
| OHM52_RS04705 (OHM52_04705) | - | 938661..939242 (+) | 582 | WP_002934983.1 | thymidine kinase | - |
| OHM52_RS04710 (OHM52_04710) | prfA | 939523..940602 (+) | 1080 | WP_002934984.1 | peptide chain release factor 1 | - |
| OHM52_RS04715 (OHM52_04715) | prmC | 940602..941435 (+) | 834 | WP_002934985.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
| OHM52_RS04720 (OHM52_04720) | - | 941422..942030 (+) | 609 | WP_009909811.1 | L-threonylcarbamoyladenylate synthase | - |
| OHM52_RS04725 (OHM52_04725) | - | 942027..942458 (+) | 432 | WP_009909813.1 | GNAT family N-acetyltransferase | - |
| OHM52_RS04730 (OHM52_04730) | glyA | 942482..943741 (+) | 1260 | WP_002934988.1 | serine hydroxymethyltransferase | - |
| OHM52_RS04735 (OHM52_04735) | - | 943741..944715 (+) | 975 | WP_002934989.1 | nucleoid-associated protein | - |
| OHM52_RS04740 (OHM52_04740) | - | 944716..945315 (+) | 600 | WP_002934990.1 | lysozyme family protein | - |
| OHM52_RS04745 (OHM52_04745) | - | 945416..946174 (+) | 759 | WP_002934991.1 | SDR family NAD(P)-dependent oxidoreductase | - |
| OHM52_RS04750 (OHM52_04750) | - | 946191..946943 (+) | 753 | WP_002934992.1 | DUF6287 domain-containing protein | - |
| OHM52_RS04755 (OHM52_04755) | - | 946940..947272 (+) | 333 | WP_002934993.1 | HIRAN domain-containing protein | - |
| OHM52_RS04760 (OHM52_04760) | - | 947293..948240 (-) | 948 | WP_009909815.1 | hypothetical protein | - |
| OHM52_RS04765 (OHM52_04765) | - | 948268..949056 (-) | 789 | WP_002934995.1 | hypothetical protein | - |
| OHM52_RS04770 (OHM52_04770) | - | 949257..950954 (+) | 1698 | WP_024394313.1 | AAA family ATPase | - |
| OHM52_RS04775 (OHM52_04775) | mcrC | 950951..952000 (+) | 1050 | WP_002934997.1 | 5-methylcytosine-specific restriction endonuclease system specificity protein McrC | - |
| OHM52_RS04780 (OHM52_04780) | guaA | 952162..953712 (-) | 1551 | WP_002934999.1 | glutamine-hydrolyzing GMP synthase | - |
| OHM52_RS04785 (OHM52_04785) | - | 953988..954686 (+) | 699 | WP_002943214.1 | GntR family transcriptional regulator | - |
| OHM52_RS04790 (OHM52_04790) | - | 954789..955121 (+) | 333 | WP_002935001.1 | putative DNA-binding protein | - |
| OHM52_RS04795 (OHM52_04795) | ffh | 955134..956708 (+) | 1575 | WP_002935002.1 | signal recognition particle protein | - |
| OHM52_RS04800 (OHM52_04800) | - | 956902..957570 (+) | 669 | WP_002935003.1 | SatD family protein | - |
| OHM52_RS04805 (OHM52_04805) | - | 957574..958314 (+) | 741 | WP_009909823.1 | DUF3307 domain-containing protein | - |
| OHM52_RS04810 (OHM52_04810) | - | 958380..958901 (+) | 522 | WP_002935005.1 | AAA family ATPase | - |
| OHM52_RS04815 (OHM52_04815) | xerS | 959068..960138 (+) | 1071 | WP_002935006.1 | tyrosine recombinase XerS | - |
| OHM52_RS04820 (OHM52_04820) | - | 960208..961716 (-) | 1509 | WP_013730362.1 | phosphoglucomutase | - |
| OHM52_RS04825 (OHM52_04825) | - | 961792..962733 (-) | 942 | WP_002935009.1 | sensor histidine kinase | - |
| OHM52_RS04830 (OHM52_04830) | - | 962730..963395 (-) | 666 | WP_009909826.1 | response regulator transcription factor | - |
| OHM52_RS04835 (OHM52_04835) | - | 963434..963640 (-) | 207 | WP_370287028.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| OHM52_RS04840 (OHM52_04840) | relB | 963681..963920 (-) | 240 | WP_002935014.1 | type II toxin-antitoxin system RelB family antitoxin | - |
| OHM52_RS04845 (OHM52_04845) | - | 964012..965983 (-) | 1972 | Protein_923 | FtsX-like permease family protein | - |
| OHM52_RS04850 (OHM52_04850) | - | 965984..966736 (-) | 753 | WP_011922409.1 | ABC transporter ATP-binding protein | - |
| OHM52_RS04855 (OHM52_04855) | - | 966872..967606 (-) | 735 | WP_011922410.1 | ABC transporter permease | - |
| OHM52_RS04860 (OHM52_04860) | - | 967608..968354 (-) | 747 | WP_011922411.1 | ABC transporter permease | - |
| OHM52_RS04865 (OHM52_04865) | - | 968356..969258 (-) | 903 | WP_011922412.1 | ABC transporter ATP-binding protein | - |
| OHM52_RS04870 (OHM52_04870) | - | 969203..969652 (-) | 450 | WP_264516791.1 | NisI/SpaI family lantibiotic immunity lipoprotein | - |
| OHM52_RS04875 (OHM52_04875) | - | 969665..969805 (-) | 141 | WP_012775106.1 | hypothetical protein | - |
| OHM52_RS04880 (OHM52_04880) | - | 969945..971111 (-) | 1167 | WP_024394863.1 | acetyl-CoA carboxylase biotin carboxylase subunit family protein | - |
| OHM52_RS04885 (OHM52_04885) | - | 971129..971854 (-) | 726 | WP_024394864.1 | esterase family protein | - |
| OHM52_RS04890 (OHM52_04890) | - | 971885..972712 (-) | 828 | WP_011922416.1 | alpha/beta hydrolase | - |
| OHM52_RS04895 (OHM52_04895) | - | 972826..973830 (-) | 1005 | WP_024394865.1 | DNA glycosylase AlkZ-like family protein | - |
| OHM52_RS04900 (OHM52_04900) | - | 973895..974730 (-) | 836 | Protein_934 | GyrI-like domain-containing protein | - |
| OHM52_RS04905 (OHM52_04905) | trmFO | 974807..976141 (-) | 1335 | WP_024394866.1 | methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO | - |
| OHM52_RS11440 | - | 976337..977088 (-) | 752 | Protein_936 | HAD family hydrolase | - |
| OHM52_RS04920 (OHM52_04920) | - | 977273..978472 (-) | 1200 | WP_014636929.1 | site-specific integrase | - |
| OHM52_RS04925 (OHM52_04925) | - | 978495..978722 (-) | 228 | WP_001258320.1 | DUF3173 family protein | - |
| OHM52_RS04930 (OHM52_04930) | - | 979001..979225 (-) | 225 | WP_014636930.1 | helix-turn-helix domain-containing protein | - |
| OHM52_RS04935 (OHM52_04935) | - | 979407..981272 (-) | 1866 | WP_014636931.1 | SAG1250 family conjugative relaxase | - |
| OHM52_RS04940 (OHM52_04940) | - | 981259..981624 (-) | 366 | WP_014636932.1 | MobC family plasmid mobilization relaxosome protein | - |
| OHM52_RS04945 (OHM52_04945) | - | 981631..981993 (-) | 363 | WP_014636933.1 | SAG1252 family conjugative relaxosome accessory protein | - |
Sequence
Protein
Download Length: 408 a.a. Molecular weight: 45318.84 Da Isoelectric Point: 4.6382
>NTDB_id=750876 OHM52_RS04670 WP_002934974.1 932369..933595(+) (clpX) [Streptococcus suis strain TRG6]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA
Nucleotide
Download Length: 1227 bp
>NTDB_id=750876 OHM52_RS04670 WP_002934974.1 932369..933595(+) (clpX) [Streptococcus suis strain TRG6]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTCATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACTGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGATACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAGCAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTTGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAGGCAATTGAACGTAAGACTGGTGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGCCAAGATAACGTTAAACGCGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTTTACTAGAAACTGCATAA
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTCATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACTGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGATACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAGCAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTTGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAGGCAATTGAACGTAAGACTGGTGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGCCAAGATAACGTTAAACGCGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTTTACTAGAAACTGCATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpX | Streptococcus mutans UA159 |
83.13 |
100 |
0.833 |
| clpX | Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 |
58.209 |
98.529 |
0.574 |