Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QEO87_RS09655 Genome accession   NZ_CP123310
Coordinates   2004416..2005072 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain AREA_C483     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1999416..2010072
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QEO87_RS09620 (QEO87_09615) dcyD 2000295..2001281 (+) 987 WP_001128208.1 D-cysteine desulfhydrase -
  QEO87_RS09625 (QEO87_09620) tcyL 2001296..2001964 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QEO87_RS09630 (QEO87_09625) tcyN 2001961..2002713 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QEO87_RS09635 (QEO87_09630) sdiA 2002943..2003665 (+) 723 WP_001152713.1 transcriptional regulator SdiA -
  QEO87_RS09640 (QEO87_09635) yecF 2003733..2003957 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QEO87_RS09645 (QEO87_09640) yecU 2003944..2004120 (-) 177 WP_000590347.1 protein YecU -
  QEO87_RS09650 - 2004203..2004274 (-) 72 Protein_1884 transcriptional regulator -
  QEO87_RS09655 (QEO87_09645) letA 2004416..2005072 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QEO87_RS09660 (QEO87_09650) uvrC 2005069..2006901 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QEO87_RS09665 (QEO87_09655) pgsA 2006958..2007506 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QEO87_RS09685 (QEO87_09675) - 2008204..2008845 (-) 642 Protein_1888 hypothetical protein -
  QEO87_RS09690 (QEO87_09680) - 2008882..2009184 (+) 303 Protein_1889 transposase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=750117 QEO87_RS09655 WP_000611328.1 2004416..2005072(+) (letA) [Escherichia coli strain AREA_C483]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=750117 QEO87_RS09655 WP_000611328.1 2004416..2005072(+) (letA) [Escherichia coli strain AREA_C483]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCAACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGTCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482