Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N4686_RS09725 Genome accession   NZ_CP123266
Coordinates   2010675..2011331 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain YZLc23-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2005675..2016331
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N4686_RS09690 (N4686_009690) dcyD 2005777..2006763 (+) 987 WP_001724631.1 D-cysteine desulfhydrase -
  N4686_RS09695 (N4686_009695) tcyL 2006778..2007446 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  N4686_RS09700 (N4686_009700) tcyN 2007443..2008195 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  N4686_RS09705 (N4686_009705) sdiA 2008425..2009147 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  N4686_RS09710 (N4686_009710) yecF 2009215..2009439 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  N4686_RS09715 (N4686_009715) yecU 2009426..2009602 (-) 177 WP_000590344.1 protein YecU -
  N4686_RS09720 (N4686_009720) - 2009696..2010393 (+) 698 WP_225528490.1 IS1-like element IS1A family transposase -
  N4686_RS25960 - 2010417..2010533 (-) 117 WP_001302039.1 hypothetical protein -
  N4686_RS09725 (N4686_009725) letA 2010675..2011331 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  N4686_RS09730 (N4686_009730) uvrC 2011328..2013160 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  N4686_RS09735 (N4686_009735) pgsA 2013217..2013765 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  N4686_RS09755 (N4686_009755) yecA 2014415..2015080 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=750034 N4686_RS09725 WP_000611335.1 2010675..2011331(+) (letA) [Escherichia coli strain YZLc23-1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=750034 N4686_RS09725 WP_000611335.1 2010675..2011331(+) (letA) [Escherichia coli strain YZLc23-1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486