Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N4683_RS09655 Genome accession   NZ_CP123247
Coordinates   1990647..1991303 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain YZMc10-2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1985647..1996303
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N4683_RS09625 (N4683_009625) dcyD 1986527..1987513 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  N4683_RS09630 (N4683_009630) tcyL 1987528..1988196 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  N4683_RS09635 (N4683_009635) tcyN 1988193..1988945 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  N4683_RS09640 (N4683_009640) sdiA 1989175..1989897 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  N4683_RS09645 (N4683_009645) yecF 1989964..1990188 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  N4683_RS09650 (N4683_009650) yecU 1990175..1990351 (-) 177 WP_000590347.1 protein YecU -
  N4683_RS25590 - 1990434..1990505 (-) 72 Protein_1891 transcriptional regulator -
  N4683_RS09655 (N4683_009655) letA 1990647..1991303 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  N4683_RS09660 (N4683_009660) uvrC 1991300..1993132 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  N4683_RS09665 (N4683_009665) pgsA 1993189..1993737 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  N4683_RS09685 (N4683_009685) - 1994433..1995173 (-) 741 Protein_1895 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=749791 N4683_RS09655 WP_000611335.1 1990647..1991303(+) (letA) [Escherichia coli strain YZMc10-2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=749791 N4683_RS09655 WP_000611335.1 1990647..1991303(+) (letA) [Escherichia coli strain YZMc10-2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486