Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N4691_RS09665 Genome accession   NZ_CP123244
Coordinates   2019709..2020365 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain YZMc3-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2014709..2025365
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N4691_RS09635 (N4691_09635) dcyD 2015589..2016575 (+) 987 WP_262940653.1 D-cysteine desulfhydrase -
  N4691_RS09640 (N4691_09640) tcyL 2016590..2017258 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  N4691_RS09645 (N4691_09645) tcyN 2017255..2018007 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  N4691_RS09650 (N4691_09650) sdiA 2018237..2018959 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  N4691_RS09655 (N4691_09655) yecF 2019026..2019250 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  N4691_RS09660 (N4691_09660) yecU 2019237..2019413 (-) 177 WP_000590347.1 protein YecU -
  N4691_RS24725 - 2019496..2019567 (-) 72 Protein_1884 transcriptional regulator -
  N4691_RS09665 (N4691_09665) letA 2019709..2020365 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  N4691_RS09670 (N4691_09670) uvrC 2020362..2022194 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  N4691_RS09675 (N4691_09675) pgsA 2022251..2022799 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  N4691_RS09695 (N4691_09695) yecA 2023448..2024113 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=749707 N4691_RS09665 WP_000611335.1 2019709..2020365(+) (letA) [Escherichia coli strain YZMc3-1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=749707 N4691_RS09665 WP_000611335.1 2019709..2020365(+) (letA) [Escherichia coli strain YZMc3-1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486