Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PAE60_RS08060 Genome accession   NZ_CP123197
Coordinates   1434280..1434936 (+) Length   218 a.a.
NCBI ID   WP_269950873.1    Uniprot ID   -
Organism   Escherichia coli strain C-SRM-3     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1429280..1439936
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PAE60_RS08030 (PAE60_008030) dcyD 1430159..1431145 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  PAE60_RS08035 (PAE60_008035) tcyL 1431160..1431828 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PAE60_RS08040 (PAE60_008040) tcyN 1431825..1432577 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PAE60_RS08045 (PAE60_008045) sdiA 1432807..1433529 (+) 723 WP_063078868.1 transcriptional regulator SdiA -
  PAE60_RS08050 (PAE60_008050) yecF 1433597..1433821 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PAE60_RS08055 (PAE60_008055) yecU 1433808..1433984 (-) 177 WP_000590344.1 protein YecU -
  PAE60_RS25670 - 1434022..1434138 (-) 117 WP_001302039.1 hypothetical protein -
  PAE60_RS08060 (PAE60_008060) letA 1434280..1434936 (+) 657 WP_269950873.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PAE60_RS08065 (PAE60_008065) uvrC 1434933..1436765 (+) 1833 WP_063078869.1 excinuclease ABC subunit UvrC Machinery gene
  PAE60_RS08070 (PAE60_008070) pgsA 1436822..1437370 (+) 549 WP_269950874.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PAE60_RS08090 (PAE60_008090) - 1438065..1438805 (-) 741 WP_063078870.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23878.69 Da        Isoelectric Point: 6.9519

>NTDB_id=749281 PAE60_RS08060 WP_269950873.1 1434280..1434936(+) (letA) [Escherichia coli strain C-SRM-3]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLCKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=749281 PAE60_RS08060 WP_269950873.1 1434280..1434936(+) (letA) [Escherichia coli strain C-SRM-3]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCTGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482