Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   QAY77_RS05335 Genome accession   NZ_CP123162
Coordinates   1088514..1090298 (+) Length   594 a.a.
NCBI ID   WP_411888780.1    Uniprot ID   -
Organism   Staphylococcus aureus strain BE-MSSA7     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1083514..1095298
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAY77_RS05315 (QAY77_05310) polX 1083633..1085345 (+) 1713 WP_000161942.1 DNA polymerase/3'-5' exonuclease PolX -
  QAY77_RS05320 (QAY77_05315) mutS/mutS2 1085355..1087703 (+) 2349 WP_411888779.1 endonuclease MutS2 Machinery gene
  QAY77_RS05325 (QAY77_05320) trxA 1087876..1088190 (+) 315 WP_001018928.1 thioredoxin -
  QAY77_RS05330 (QAY77_05325) - 1088253..1088348 (-) 96 WP_001788625.1 hypothetical protein -
  QAY77_RS05335 (QAY77_05330) uvrC 1088514..1090298 (+) 1785 WP_411888780.1 excinuclease ABC subunit UvrC Machinery gene
  QAY77_RS05340 (QAY77_05335) - 1090622..1091236 (+) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  QAY77_RS05345 (QAY77_05340) sdhA 1091288..1093054 (+) 1767 WP_000818278.1 succinate dehydrogenase flavoprotein subunit -
  QAY77_RS05350 (QAY77_05345) sdhB 1093054..1093869 (+) 816 WP_000139712.1 succinate dehydrogenase iron-sulfur subunit -
  QAY77_RS05355 (QAY77_05350) racE 1094105..1094905 (+) 801 WP_001039659.1 glutamate racemase -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68785.46 Da        Isoelectric Point: 9.7058

>NTDB_id=748933 QAY77_RS05335 WP_411888780.1 1088514..1090298(+) (uvrC) [Staphylococcus aureus strain BE-MSSA7]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSIYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEM
IQSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVS
AMVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPV
AGLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGNKRKTLLLRS
FGSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=748933 QAY77_RS05335 WP_411888780.1 1088514..1090298(+) (uvrC) [Staphylococcus aureus strain BE-MSSA7]
TTGGAAGACTATAAGCAACGAATTAAAAATAAATTAAATGTCGTACCTATGGAACCAGGATGCTATTTAATGAAAGATCG
TAATGATCAAGTGATATATGTTGGCAAAGCTAAAAAGCTAAGAAATCGATTGCGATCATATTTTACGGGTGCTCATGATG
CTAAAACAACGAGACTGGTTGGTGAAATACGTCGCTTTGAGTTTATTGTCACGTCAAGTGAAACAGAATCACTTTTACTG
GAATTGAATCTGATTAAACAATATCAACCAAGATATAATATATTATTAAAGGATGATAAAAGTTATCCATTTATTAAAAT
TACGAAGGAGAAATATCCTAGACTACTAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTATATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGGGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTGACAAACAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATAGTGTTGATAAAGGATGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAGCGAGATACAACGATGATTCCATTACAGCAAACAGAAGAAGAAGAAGAATTTTATACAT
TTATTGGACAATTTTATAGCTTAAACCAACATATTTTACCTAAGGAAGTTCATGTACCACGTAATTTGGATAAAGAAATG
ATTCAATCTGTTGTGGACACTAAAATCGTTCAACCCGCGCGAGGTCCCAAAAAAGATATGGTTGACCTAGCTGCACATAA
CGCTAAAGTATCCTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCCAGAACGATTAAAGCTATTGAAGAACTTG
GAACACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATTCAAGGTGTGGATCCAGTGTCA
GCAATGGTTACATTTGTCGACGGTAAACCAGATAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGA
TGATTACAAATCAATGAGAGAAGTAGTAAGACGACGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCTGATTTAA
TAATAGTAGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTT
GCAGGTTTGCAGAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAA
AAATAGCCAGGCATTTTATTTGTTGCACCGTATCCAAGATGAGGTTCACAGATTCGCAATCACATTTCATAGACAAACAC
GTCAAAAGACAGGCTTGAAATCAATACTTGATGATATAGATGGTATCGGTAACAAACGTAAAACATTATTATTGCGTTCA
TTCGGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATATAGGTATTCCTGAAAACGTCGCAAAGAA
CCTACATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(19-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(380-527)

UvrB/uvrC motif (UVR)

(200-233)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

57.338

98.653

0.566
  uvrC Streptococcus pneumoniae R6

57.338

98.653

0.566
  uvrC Streptococcus pneumoniae D39

57.338

98.653

0.566