Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   OF800_RS02480 Genome accession   NZ_CP109636
Coordinates   481212..481895 (+) Length   227 a.a.
NCBI ID   WP_004259224.1    Uniprot ID   A0A1I4FNQ8
Organism   Lactococcus garvieae strain Alexii-6_2     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 476212..486895
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OF800_RS02470 (OF800_02470) rpoC 476319..479966 (+) 3648 WP_004259228.1 DNA-directed RNA polymerase subunit beta' -
  OF800_RS02475 (OF800_02475) - 480060..480968 (-) 909 WP_264308508.1 diacylglycerol kinase family protein -
  OF800_RS02480 (OF800_02480) mecA 481212..481895 (+) 684 WP_004259224.1 adaptor protein MecA Regulator
  OF800_RS02485 (OF800_02485) - 481899..483155 (+) 1257 WP_264308509.1 MraY family glycosyltransferase -
  OF800_RS02490 (OF800_02490) sufC 483233..484003 (+) 771 WP_264308510.1 Fe-S cluster assembly ATPase SufC -
  OF800_RS02495 (OF800_02495) sufD 484075..485331 (+) 1257 WP_019299087.1 Fe-S cluster assembly protein SufD -
  OF800_RS02500 (OF800_02500) - 485331..486542 (+) 1212 WP_264308511.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26239.38 Da        Isoelectric Point: 4.0202

>NTDB_id=748685 OF800_RS02480 WP_004259224.1 481212..481895(+) (mecA) [Lactococcus garvieae strain Alexii-6_2]
MQYEEINEKTIKISLTFQDLVDHDVKLSDFFTNQSMVENLFYELVEELGLEERFSSGLLTFQIQPFPKGVNIIVTEENID
IDPNNLPDDPEEFEQLMTDFFGRVEDLKQNGGTMADTSTTETKETKVENKPDPDFVFYSLEFENMSQLLTAVKNVKIDAE
ESELYSYQDKFYLIILDNQKSKGKTAVSSMRARMLEYGQETVNSRETLQEYGEILINTRALEVLSKI

Nucleotide


Download         Length: 684 bp        

>NTDB_id=748685 OF800_RS02480 WP_004259224.1 481212..481895(+) (mecA) [Lactococcus garvieae strain Alexii-6_2]
ATGCAATACGAAGAAATAAACGAAAAAACGATAAAGATTAGCCTAACCTTTCAAGATTTGGTTGATCATGATGTCAAACT
CTCTGATTTTTTTACTAACCAGTCAATGGTTGAAAATCTTTTTTATGAATTAGTAGAAGAGCTAGGACTTGAGGAAAGAT
TCTCATCAGGACTTTTAACTTTCCAAATTCAACCTTTCCCTAAAGGGGTGAATATCATTGTTACTGAGGAAAACATTGAT
ATTGATCCCAATAATCTCCCGGATGATCCTGAAGAATTTGAGCAGCTGATGACGGATTTCTTTGGGCGTGTGGAAGATTT
AAAACAAAATGGCGGAACAATGGCAGATACAAGTACAACTGAAACGAAAGAAACAAAAGTAGAAAATAAACCAGACCCAG
ATTTTGTCTTCTATTCTCTAGAATTTGAAAATATGTCTCAACTTTTGACAGCGGTAAAAAATGTTAAAATTGATGCAGAA
GAGTCTGAACTTTACAGTTACCAAGATAAGTTTTATTTGATTATTTTGGACAATCAAAAATCAAAAGGAAAAACAGCCGT
AAGTTCGATGCGTGCCCGAATGTTAGAATACGGCCAGGAAACGGTCAACAGTCGTGAAACCCTACAAGAATACGGCGAGA
TACTAATCAATACGCGTGCTTTGGAAGTTCTCTCAAAAATTTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1I4FNQ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. cremoris KW2

54.661

100

0.568
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

54.077

100

0.555