Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   KUH140013_RS11345 Genome accession   NZ_AP020324
Coordinates   2244920..2245585 (+) Length   221 a.a.
NCBI ID   WP_000697877.1    Uniprot ID   A0A0D1JN68
Organism   Staphylococcus aureus strain KUN1163     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2239920..2250585
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KUH140013_RS11320 (KUN1163_2116) - 2241328..2242089 (+) 762 WP_000323441.1 alpha/beta hydrolase -
  KUH140013_RS11325 (KUN1163_2117) - 2242334..2242789 (+) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  KUH140013_RS15390 (KUN1163_2118) - 2242911..2243012 (+) 102 WP_000731976.1 SE2200 family small protein -
  KUH140013_RS11335 (KUN1163_2119) - 2243072..2244496 (-) 1425 WP_000953755.1 alkaline phosphatase -
  KUH140013_RS11340 (KUN1163_2120) - 2244694..2244894 (+) 201 WP_000604730.1 hypothetical protein -
  KUH140013_RS11345 (KUN1163_2121) braR 2244920..2245585 (+) 666 WP_000697877.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  KUH140013_RS11350 (KUN1163_2122) braS 2245596..2246483 (+) 888 WP_000143425.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  KUH140013_RS11355 (KUN1163_2123) - 2246591..2247346 (+) 756 WP_000923760.1 ABC transporter ATP-binding protein -
  KUH140013_RS11360 (KUN1163_2124) - 2247343..2249343 (+) 2001 WP_000776751.1 ABC transporter permease -
  KUH140013_RS11365 - 2250002..2250115 (+) 114 Protein_2169 hypothetical protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25415.49 Da        Isoelectric Point: 4.7961

>NTDB_id=74864 KUH140013_RS11345 WP_000697877.1 2244920..2245585(+) (braR) [Staphylococcus aureus strain KUN1163]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSLTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=74864 KUH140013_RS11345 WP_000697877.1 2244920..2245585(+) (braR) [Staphylococcus aureus strain KUN1163]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAGCCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCATTGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0D1JN68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

100

100

1

Multiple sequence alignment