Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | KUH140013_RS10580 | Genome accession | NZ_AP020324 |
| Coordinates | 2079881..2081509 (+) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain KUN1163 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 2074320..2108391 | 2079881..2081509 | within | 0 |
| SCCmec | 2078510..2099875 | 2079881..2081509 | within | 0 |
Gene organization within MGE regions
Location: 2074320..2108391
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KUH140013_RS10560 (KUN1163_1970) | - | 2074948..2075994 (+) | 1047 | WP_001060127.1 | hypothetical protein | - |
| KUH140013_RS10565 (KUN1163_1971) | ssb | 2076187..2076483 (+) | 297 | WP_000273824.1 | cassette chromosome ssDNA-binding protein | - |
| KUH140013_RS10570 (KUN1163_1972) | cch1 | 2076483..2078276 (+) | 1794 | WP_000195100.1 | cassette chromosome replicative helicase | - |
| KUH140013_RS10575 (KUN1163_1973) | ccrA | 2078510..2079859 (+) | 1350 | WP_000815646.1 | cassette chromosome recombinase CcrA | Machinery gene |
| KUH140013_RS10580 (KUN1163_1974) | ccrB | 2079881..2081509 (+) | 1629 | WP_001186602.1 | cassette chromosome recombinase CcrB | Machinery gene |
| KUH140013_RS10585 (KUN1163_1975) | - | 2082027..2082377 (+) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KUH140013_RS10590 (KUN1163_1977) | - | 2082464..2082775 (+) | 312 | WP_000700853.1 | DUF960 family protein | - |
| KUH140013_RS10595 (KUN1163_1978) | - | 2082793..2083299 (+) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| KUH140013_RS10600 (KUN1163_1979) | - | 2083320..2083637 (+) | 318 | WP_061641403.1 | JAB domain-containing protein | - |
| KUH140013_RS10605 (KUN1163_1980) | - | 2083756..2084841 (+) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| KUH140013_RS10610 (KUN1163_1981) | - | 2084838..2086730 (+) | 1893 | WP_001557544.1 | site-specific integrase | - |
| KUH140013_RS10615 (KUN1163_1982) | - | 2086737..2087114 (+) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| KUH140013_RS10620 (KUN1163_1983) | - | 2087265..2088047 (+) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| KUH140013_RS10625 (KUN1163_1984) | erm(A) | 2088173..2088904 (-) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| KUH140013_RS15480 | - | 2088987..2089046 (-) | 60 | WP_010959190.1 | erythromycin resistance leader peptide | - |
| KUH140013_RS10640 (KUN1163_1985) | - | 2089438..2090100 (+) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| KUH140013_RS10650 (KUN1163_1986) | - | 2090445..2091083 (-) | 639 | Protein_2033 | sulfite exporter TauE/SafE family protein | - |
| KUH140013_RS10655 (KUN1163_1987) | cstR | 2091083..2091343 (-) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| KUH140013_RS10660 (KUN1163_1988) | - | 2091479..2092543 (+) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| KUH140013_RS10665 (KUN1163_1989) | cstB | 2092576..2093910 (+) | 1335 | Protein_2036 | persulfide dioxygenase-sulfurtransferase CstB | - |
| KUH140013_RS10675 (KUN1163_1991) | - | 2094024..2095133 (-) | 1110 | WP_000943131.1 | ROK family transcriptional regulator | - |
| KUH140013_RS10680 | psm-mec | 2095488..2095556 (+) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| KUH140013_RS10685 (KUN1163_1992) | mecI | 2095641..2096012 (-) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| KUH140013_RS10690 (KUN1163_1993) | mecR1 | 2096012..2097769 (-) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| KUH140013_RS10695 (KUN1163_1994) | mecA | 2097866..2099875 (+) | 2010 | WP_078369868.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| KUH140013_RS10700 (KUN1163_1995) | - | 2099921..2100349 (-) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| KUH140013_RS10705 (KUN1163_1996) | - | 2100446..2101189 (-) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| KUH140013_RS10715 | - | 2101946..2102335 (-) | 390 | WP_020444595.1 | hydroxymethylglutaryl-CoA synthase | - |
| KUH140013_RS10720 (KUN1163_1998) | - | 2102371..2103045 (+) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| KUH140013_RS10725 (KUN1163_1999) | aadD1 | 2103247..2104008 (+) | 762 | WP_001014230.1 | aminoglycoside O-nucleotidyltransferase ANT(4')-Ia | - |
| KUH140013_RS10730 (KUN1163_2000) | bleO | 2104225..2104629 (+) | 405 | WP_001242578.1 | bleomycin binding protein | - |
| KUH140013_RS10735 (KUN1163_2001) | mobV | 2105136..2106398 (+) | 1263 | WP_000119405.1 | MobV family relaxase | - |
| KUH140013_RS10740 (KUN1163_2002) | - | 2106643..2107626 (+) | 984 | Protein_2049 | protein rep | - |
| KUH140013_RS10750 (KUN1163_2004) | - | 2107717..2108391 (+) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=74861 KUH140013_RS10580 WP_001186602.1 2079881..2081509(+) (ccrB) [Staphylococcus aureus strain KUN1163]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=74861 KUH140013_RS10580 WP_001186602.1 2079881..2081509(+) (ccrB) [Staphylococcus aureus strain KUN1163]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |