Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   QAY79_RS05805 Genome accession   NZ_CP123154
Coordinates   1203833..1205614 (+) Length   593 a.a.
NCBI ID   WP_411896959.1    Uniprot ID   -
Organism   Staphylococcus aureus strain GE-MRSA17     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1198833..1210614
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAY79_RS05785 (QAY79_05805) polX 1198952..1200664 (+) 1713 WP_000161938.1 DNA polymerase/3'-5' exonuclease PolX -
  QAY79_RS05790 (QAY79_05810) mutS/mutS2 1200674..1203022 (+) 2349 WP_001249272.1 endonuclease MutS2 Machinery gene
  QAY79_RS05795 (QAY79_05815) trxA 1203195..1203509 (+) 315 WP_001018928.1 thioredoxin -
  QAY79_RS05800 (QAY79_05820) - 1203572..1203667 (-) 96 WP_001788625.1 hypothetical protein -
  QAY79_RS05805 (QAY79_05825) uvrC 1203833..1205614 (+) 1782 WP_411896959.1 excinuclease ABC subunit UvrC Machinery gene
  QAY79_RS05810 (QAY79_05830) - 1205938..1206552 (+) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  QAY79_RS05815 (QAY79_05835) sdhA 1206604..1208370 (+) 1767 WP_000818278.1 succinate dehydrogenase flavoprotein subunit -
  QAY79_RS05820 (QAY79_05840) sdhB 1208370..1209185 (+) 816 WP_000139712.1 succinate dehydrogenase iron-sulfur subunit -
  QAY79_RS05825 (QAY79_05845) racE 1209421..1210221 (+) 801 WP_001039659.1 glutamate racemase -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68687.46 Da        Isoelectric Point: 9.7823

>NTDB_id=748576 QAY79_RS05805 WP_411896959.1 1203833..1205614(+) (uvrC) [Staphylococcus aureus strain GE-MRSA17]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIKNLTNKQKI
MSSDKTIRDVFGYCVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMI
QSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSA
MVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVA
GLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGNKRKTLLLRSF
GSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=748576 QAY79_RS05805 WP_411896959.1 1203833..1205614(+) (uvrC) [Staphylococcus aureus strain GE-MRSA17]
TTGGAAGACTATAAGCAACGAATTAAAAATAAATTAAATGTCGTACCTATGGAACCAGGCTGCTATTTAATGAAAGATCG
TAATGATCAAGTGATATATGTTGGCAAAGCTAAAAAGCTAAGAAATCGATTGAGATCATATTTTACGGGTGCTCATGATG
CTAAAACAACGAGACTGGTTGGTGAAATACGTCGTTTTGAGTTTATTGTCACGTCAAGTGAAACAGAGTCACTTTTACTG
GAATTGAATCTGATAAAACAATATCAACCAAGATATAATATATTATTAAAGGATGATAAAAGTTATCCATTTATTAAAAT
TACGAAGGAGAAATATCCTAGACTACTAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAAATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGGGCTAAAGAATATAGAGATTTAATTCAACATATTAAAAATCTGACAAACAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATTGTGTTGATAAAGGATGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAGCGAGATACAACGATGATTCCATTACAGCAAACAGAAGAAGAAGAATTTTATACATTTA
TTGGACAATTTTATAGCTTAAACCAACATATTTTACCTAAGGAAGTTCATGTACCACGTAATTTGGATAAAGAAATGATT
CAATCTGTTGTGGACACTAAAATCGTTCAACCCGCGCGAGGTCCCAAAAAAGATATGGTTGACCTAGCTGCACATAACGC
TAAAGTATCCTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCAAGAACGATTAAAGCTATTGAAGAACTTGGAA
CACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATTCAAGGTGTGGATCCAGTGTCAGCA
ATGGTTACATTTGTCGACGGTAAACCAGATAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGATGA
TTACAAATCAATGAGAGAAGTAGTAAGACGACGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCTGATTTAATAA
TAGTCGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
GGTTTGCAGAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAAAAA
TAGCCAGGCATTTTATTTGTTGCATCGTATCCAAGATGAGGTTCACAGATTCGCAATCACATTTCATAGACAAACACGTC
AAAAGACAGGCTTGAAATCAATACTTGATGATATAGATGGTATCGGTAACAAACGTAAAACATTATTATTGCGTTCATTC
GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATATAGGTATTCCTGAAAACGTCGCAAAGAACCT
ACATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(200-233)

GIY-YIG catalytic domain (GIY-YIG)

(19-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-526)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

57.436

98.651

0.567
  uvrC Streptococcus pneumoniae R6

57.436

98.651

0.567
  uvrC Streptococcus pneumoniae D39

57.436

98.651

0.567