Detailed information NTG0074851

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: KUH140013_RS06005
• Genome accession: NZ_AP020324
• Coordinates: 1147149..1148135 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain KUN1163
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1142149..1153135

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KUH140013_RS05980 (KUN1163_1117)	-	1142409..1142756 (-)	348	WP_001242103.1	hypothetical protein	-
KUH140013_RS05985 (KUN1163_1118)	-	1142942..1143535 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
KUH140013_RS05990 (KUN1163_1119)	-	1143639..1144004 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
KUH140013_RS05995 (KUN1163_1120)	yjbH	1144027..1144833 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
KUH140013_RS06000 (KUN1163_1121)	pepF	1145293..1147101 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
KUH140013_RS06005 (KUN1163_1122)	coiA	1147149..1148135 (-)	987	WP_000959282.1	competence protein CoiA	Machinery gene
KUH140013_RS06010 (KUN1163_1123)	mecA	1148256..1148975 (-)	720	WP_001217728.1	adaptor protein MecA	-
KUH140013_RS06015 (KUN1163_1124)	spxA	1149346..1149741 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
KUH140013_RS06020 (KUN1163_1125)	trpS	1150035..1151024 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
KUH140013_RS06025 (KUN1163_1126)	opp4C	1151066..1151947 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
KUH140013_RS06030 (KUN1163_1127)	opp4B	1151959..1152921 (-)	963	WP_150013937.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=74851 KUH140013_RS06005 WP_000959282.1 1147149..1148135(-) (coiA) [Staphylococcus aureus strain KUN1163]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=74851 KUH140013_RS06005 WP_000959282.1 1147149..1148135(-) (coiA) [Staphylococcus aureus strain KUN1163]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976