Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   F6Y14_RS08165 Genome accession   NZ_AP020322
Coordinates   1569936..1570505 (-) Length   189 a.a.
NCBI ID   WP_000872882.1    Uniprot ID   A0A7U7EXA1
Organism   Staphylococcus aureus strain KUH180129     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1564936..1575505
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F6Y14_RS08120 - 1565411..1566018 (-) 608 Protein_1540 class I SAM-dependent methyltransferase -
  F6Y14_RS08125 (KUH180129_1526) rplL 1566193..1566561 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  F6Y14_RS08130 (KUH180129_1527) rplJ 1566604..1567104 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  F6Y14_RS08140 (KUH180129_1528) rplA 1567376..1568068 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  F6Y14_RS08145 (KUH180129_1529) rplK 1568276..1568698 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  F6Y14_RS08150 (KUH180129_1530) nusG 1568879..1569427 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  F6Y14_RS08155 (KUH180129_1531) secE 1569440..1569622 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  F6Y14_RS08160 rpmG 1569678..1569821 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  F6Y14_RS08165 (KUH180129_1532) sigH 1569936..1570505 (-) 570 WP_000872882.1 sigma-70 family RNA polymerase sigma factor Regulator
  F6Y14_RS08170 (KUH180129_1533) - 1570586..1571110 (-) 525 WP_000664737.1 NYN domain-containing protein -
  F6Y14_RS08175 (KUH180129_1534) rlmB 1571110..1571856 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  F6Y14_RS08180 (KUH180129_1535) - 1571864..1572268 (-) 405 WP_000370182.1 Mini-ribonuclease 3 -
  F6Y14_RS08185 (KUH180129_1536) cysS 1572261..1573661 (-) 1401 WP_150073924.1 cysteine--tRNA ligase -
  F6Y14_RS08190 (KUH180129_1537) cysE 1573645..1574292 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23044.91 Da        Isoelectric Point: 9.4170

>NTDB_id=74814 F6Y14_RS08165 WP_000872882.1 1569936..1570505(-) (sigH) [Staphylococcus aureus strain KUH180129]
MKYDLTTQDSTIKRNNSINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=74814 F6Y14_RS08165 WP_000872882.1 1569936..1570505(-) (sigH) [Staphylococcus aureus strain KUH180129]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATTCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXA1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

100

100

1
  sigH Staphylococcus aureus MW2

97.884

100

0.979

Multiple sequence alignment