Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   K6K00_RS02880 Genome accession   NZ_AP024628
Coordinates   558945..559586 (+) Length   213 a.a.
NCBI ID   WP_003244318.1    Uniprot ID   P96686
Organism   Bacillus subtilis strain BEST3145     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 553945..564586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6K00_RS02850 (BsBEST3145_05350) ydfE 555140..555763 (-) 624 WP_003243530.1 flavin reductase family protein -
  K6K00_RS02855 (BsBEST3145_05360) ydfF 555853..556533 (+) 681 WP_003244115.1 helix-turn-helix transcriptional regulator -
  K6K00_RS02860 (BsBEST3145_05370) ydfG 556613..557056 (-) 444 WP_003242768.1 carboxymuconolactone decarboxylase family protein -
  K6K00_RS02865 (BsBEST3145_05380) - 557142..557321 (-) 180 WP_010886421.1 hypothetical protein -
  K6K00_RS02870 - 557318..557461 (-) 144 WP_003243880.1 hypothetical protein -
  K6K00_RS02875 (BsBEST3145_05390) ydfH 557729..558952 (+) 1224 WP_010886422.1 two-component system sensor histidine kinase YdfH -
  K6K00_RS02880 (BsBEST3145_05400) vraR 558945..559586 (+) 642 WP_003244318.1 two-component system response regulator YdfI Regulator
  K6K00_RS02885 (BsBEST3145_05410) pleJ 559702..561876 (+) 2175 WP_003243548.1 MMPL family transporter -
  K6K00_RS02890 (BsBEST3145_05420) cesA 562288..563190 (-) 903 WP_003242638.1 carboxylesterase -
  K6K00_RS02895 (BsBEST3145_05430) ydfK 563392..564081 (-) 690 WP_003242513.1 DUF554 domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23973.92 Da        Isoelectric Point: 5.4183

>NTDB_id=74597 K6K00_RS02880 WP_003244318.1 558945..559586(+) (vraR) [Bacillus subtilis strain BEST3145]
MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIIL
TTYNEDHLMIEGIELGAKGYLLKDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRNETQLTEKEVIVLKAI
AKGLKSKAIAFDLGVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=74597 K6K00_RS02880 WP_003244318.1 558945..559586(+) (vraR) [Bacillus subtilis strain BEST3145]
ATGAATAAGGTTTTAATCGTTGATGACCATCTTGTCGTGAGGGAAGGTCTGAAGCTTTTAATTGAAACGAATGATCAATA
CACCATTATAGGAGAGGCGGAAAATGGAAAAGTAGCAGTCCGTCTTGCAGATGAATTAGAACCGGATATCATTCTGATGG
ATTTGTATATGCCGGAGATGAGCGGGTTAGAGGCCATTAAACAAATAAAAGAAAAACACGATACCCCCATCATTATTTTG
ACTACATATAATGAAGATCACTTAATGATCGAAGGGATTGAATTAGGAGCGAAAGGATATCTGTTAAAAGATACGAGTTC
AGAAACCCTTTTTCACACAATGGATGCAGCCATCAGAGGAAATGTGCTATTGCAGCCTGATATCCTTAAACGTCTGCAAG
AAATCCAATTTGAGCGGATGAAAAAGCAGCGCAATGAGACGCAGCTGACAGAAAAGGAAGTCATTGTTCTAAAAGCAATT
GCTAAAGGTCTTAAAAGCAAAGCGATTGCCTTTGATTTGGGCGTCTCTGAGCGAACAGTAAAGTCCAGATTAACGTCCAT
TTACAATAAATTAGGCGCGAATTCAAGAACTGAGGCAGTAACGATTGCCATGCAAAAAGGTATTCTGACAATAGACAACT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P96686

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.493

99.061

0.362

Multiple sequence alignment