Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QEN57_RS09580 Genome accession   NZ_CP123029
Coordinates   1993079..1993735 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 20-20     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1988079..1998735
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QEN57_RS09550 dcyD 1988958..1989944 (+) 987 WP_001128218.1 D-cysteine desulfhydrase -
  QEN57_RS09555 tcyL 1989959..1990627 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QEN57_RS09560 tcyN 1990624..1991376 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QEN57_RS09565 sdiA 1991606..1992328 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  QEN57_RS09570 yecF 1992396..1992620 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QEN57_RS09575 yecU 1992607..1992783 (-) 177 WP_000590347.1 protein YecU -
  QEN57_RS24425 - 1992866..1992937 (-) 72 Protein_1872 transcriptional regulator -
  QEN57_RS09580 letA 1993079..1993735 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QEN57_RS09585 uvrC 1993732..1995564 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QEN57_RS09590 pgsA 1995621..1996169 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QEN57_RS09610 yecA 1996819..1997484 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=745147 QEN57_RS09580 WP_000611335.1 1993079..1993735(+) (letA) [Escherichia coli strain 20-20]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=745147 QEN57_RS09580 WP_000611335.1 1993079..1993735(+) (letA) [Escherichia coli strain 20-20]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486