Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QEN53_RS09725 Genome accession   NZ_CP123024
Coordinates   2015001..2015657 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 20-16     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2010001..2020657
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QEN53_RS09695 dcyD 2010880..2011866 (+) 987 WP_001128218.1 D-cysteine desulfhydrase -
  QEN53_RS09700 tcyL 2011881..2012549 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QEN53_RS09705 tcyN 2012546..2013298 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QEN53_RS09710 sdiA 2013528..2014250 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  QEN53_RS09715 yecF 2014318..2014542 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QEN53_RS09720 yecU 2014529..2014705 (-) 177 WP_000590347.1 protein YecU -
  QEN53_RS24085 - 2014788..2014859 (-) 72 Protein_1901 transcriptional regulator -
  QEN53_RS09725 letA 2015001..2015657 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QEN53_RS09730 uvrC 2015654..2017486 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QEN53_RS09735 pgsA 2017543..2018091 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QEN53_RS09755 yecA 2018741..2019406 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=745066 QEN53_RS09725 WP_000611335.1 2015001..2015657(+) (letA) [Escherichia coli strain 20-16]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=745066 QEN53_RS09725 WP_000611335.1 2015001..2015657(+) (letA) [Escherichia coli strain 20-16]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486