Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QEN56_RS09740 Genome accession   NZ_CP123013
Coordinates   2018304..2018960 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 18-4     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2013304..2023960
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QEN56_RS09710 dcyD 2014183..2015169 (+) 987 WP_001128218.1 D-cysteine desulfhydrase -
  QEN56_RS09715 tcyL 2015184..2015852 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QEN56_RS09720 tcyN 2015849..2016601 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QEN56_RS09725 sdiA 2016831..2017553 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  QEN56_RS09730 yecF 2017621..2017845 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QEN56_RS09735 yecU 2017832..2018008 (-) 177 WP_000590347.1 protein YecU -
  QEN56_RS24145 - 2018091..2018162 (-) 72 Protein_1904 transcriptional regulator -
  QEN56_RS09740 letA 2018304..2018960 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QEN56_RS09745 uvrC 2018957..2020789 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QEN56_RS09750 pgsA 2020846..2021394 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QEN56_RS09770 yecA 2022044..2022709 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=744902 QEN56_RS09740 WP_000611335.1 2018304..2018960(+) (letA) [Escherichia coli strain 18-4]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=744902 QEN56_RS09740 WP_000611335.1 2018304..2018960(+) (letA) [Escherichia coli strain 18-4]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486