Detailed information NTG0744181

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: QAD57_RS00150
• Genome accession: NZ_CP122947
• Coordinates: 42540..45098 (-)
• Length: 852 a.a.
• NCBI ID: WP_286445837.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain BS07
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 37540..50098

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAD57_RS00130 (QAD57_00130)	comB10	38352..39554 (-)	1203	WP_140528722.1	DNA type IV secretion system protein ComB10	Machinery gene
QAD57_RS00135 (QAD57_00135)	-	39551..41227 (-)	1677	Protein_27	TrbG/VirB9 family P-type conjugative transfer protein	-
QAD57_RS00140 (QAD57_00140)	-	41224..42393 (-)	1170	WP_286445836.1	VirB8/TrbF family protein	-
QAD57_RS00145 (QAD57_00145)	-	42386..42520 (-)	135	WP_000738749.1	hypothetical protein	-
QAD57_RS00150 (QAD57_00150)	comB4	42540..45098 (-)	2559	WP_286445837.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
QAD57_RS00155 (QAD57_00155)	-	45098..45334 (-)	237	WP_180521129.1	hypothetical protein	-
QAD57_RS00160 (QAD57_00160)	comB3	45345..45608 (-)	264	WP_001177713.1	hypothetical protein	Machinery gene
QAD57_RS00165 (QAD57_00165)	comB2	45619..45903 (-)	285	WP_286445838.1	TrbC/VirB2 family protein	Machinery gene
QAD57_RS00170 (QAD57_00170)	-	45900..46379 (-)	480	WP_180598625.1	hypothetical protein	-
QAD57_RS00175 (QAD57_00175)	-	46483..47271 (-)	789	WP_120945486.1	integrase	-
QAD57_RS00180 (QAD57_00180)	-	47319..47978 (-)	660	WP_286445839.1	DEAD/DEAH box helicase family protein	-
QAD57_RS00185 (QAD57_00185)	-	48034..48168 (+)	135	WP_001146209.1	hypothetical protein	-
QAD57_RS00190 (QAD57_00190)	-	48152..48836 (-)	685	Protein_38	type I restriction endonuclease	-

Sequence

Protein

• Length: 852 a.a.
• Molecular weight: 98129.86 Da
• Isoelectric Point: 8.3448

>NTDB_id=744181 QAD57_RS00150 WP_286445837.1 42540..45098(-) (comB4) [Helicobacter pylori strain BS07]
MFENALKYCKEKAIDLLTGFVPKTYSMTEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEES
SKENKQENENSSNETHSNTSSNKDKKNKFKKKTTFSATSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNIHFKKDYFIIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESL
NFLKTKKKLTLSKIVKNDIDDYIELVQANRLSMQECALNLVLRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKLSYF
SFFPNNANINPRMRNQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGTTGAGKTTLISYLMMSALKYPNIDILALDRLNGLYSFTKYFDGIYNEGESFHINPFSLEDSASNRAFLLHFYAQM
AKVDSYDKHNDKIEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNSIVKTNTNILDSSFEYYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDDDAGLLAYYVFHKMIDRDLKINRGFLCFIDEFKSYAQNEMINKEINKIITQARKANG
VIVLALQDINQLSEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIENLIKHYPTTWKEVFVNNTYQKFDDKNT

Nucleotide

• Length: 2559 bp

>NTDB_id=744181 QAD57_RS00150 WP_286445837.1 42540..45098(-) (comB4) [Helicobacter pylori strain BS07]
ATGTTTGAAAACGCTCTTAAATATTGTAAAGAAAAAGCCATAGACCTTTTAACAGGTTTTGTTCCAAAAACCTATTCTAT
GACAGAGGAATGCAATATTTTAGGTTTGTATGATGATACTTTCATCATCACTAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCAAACTTAATGCAAAAAGATTTGGAGGGCTATTTTGATACAAGGCAAAATGTTTTAAAC
ACCATTAGTAAAGACATTCAATTAAGGATTGTCGCTAAAAGGCGTAAAGAATTTATCAACCAAAGCCCAAATATTGATAA
CCCATACGCAAAAGCCATTATCACGCAATTTGAGAGCAAGGAAATCTACAAAACAGAGTATTTTTTAGTGTTTGAGAGCA
TTACTTCTAATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGC
TCTAAAGAGAATAAACAAGAGAATGAAAATAGCTCCAATGAGACCCATTCAAATACAAGCTCTAACAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGACAACCTTTAGTGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTGAAAAACG
CATTAAGGGAGTTTAAACCCACTCTTTTAAATTCTAAAGAAGTGTTGAATTTTTATGCAGAATATATCAATGGCAAATAC
ATCGCCTTTAATCCTAAATTAAAGCGACTAAGCGATAGCTATATCGCTAGTAATATCCATTTTAAAAAAGATTATTTCAT
CATTGAATTTCAAAATCAAAGCACTTTTTGTGCGTGTGTGGGGATTAAAAACTATGAGAGTGAAGAAATTTCTTCACTCC
CCATTTCCACCCTTTTACACACTCAAATTGAATTAGATTTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGCTTG
AATTTTTTAAAAACCAAGAAAAAGCTCACGCTTTCTAAAATCGTTAAAAATGATATTGATGATTATATAGAATTGGTGCA
AGCCAATCGTTTGAGTATGCAAGAGTGTGCCTTAAACTTAGTTTTAAGAGCTAAAAGTAAAGCAAAACTAGATAAGTCTT
TAAAAGAGATTTTATCTTTACTCAATAACGCTGGACTAGGCAGTGTTACAGAAACCATAGGGCTAAAACTCTCTTATTTT
TCTTTTTTTCCTAATAACGCCAATATCAATCCTAGAATGAGAAATCAAACTTCCCAAGTGATTGCCTCTTTAATCTTGTT
TGAGAAAAATAATACAGGTTTTAGGGCAAATTCATGGGGGGATATGCCCTTATCTGTGTTTAAGAACCTAGACCATAGCC
CTTATTTGTTTAACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCCCATAATGTGGCACGAGTGGTAGGACAT
ACCATGATTATTGGCACAACAGGAGCTGGTAAAACCACGCTCATTAGCTATTTGATGATGAGCGCTTTAAAATACCCTAA
CATTGACATTCTAGCTCTTGATAGATTAAATGGCTTGTATTCTTTTACCAAGTATTTTGATGGGATCTATAATGAAGGCG
AAAGCTTTCATATTAATCCTTTTTCATTAGAAGATAGTGCAAGTAACAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTAGATAGCTATGACAAACATAATGATAAGATAGAAGATAGAACAGCCCTTTTAAACGCTATTGATACCATGTA
TAGAAATTATAACGATGAAGTCAAACAAGCCAAATTTAGCAACCAAGAATTACCACTCCCTTTTGATTTAAAAGAGTTTG
TCAATTCCATTGTTAAAACCAATACAAACATTTTAGATAGCAGTTTTGAATACTATTTAAAATCTTCCTTATTTTCTAGC
CGAATGGATAGCCTAGATTTTAAAACTCGTATTAGCACCATAAATACTGATAGCATTTTACACAATGATGATGACGCTGG
GCTTTTAGCTTATTATGTGTTTCATAAGATGATTGATAGAGATTTGAAAATCAATCGTGGGTTTTTATGTTTTATTGATG
AGTTTAAATCTTACGCTCAAAATGAAATGATAAATAAAGAAATCAATAAAATCATCACGCAAGCTAGAAAGGCTAATGGG
GTCATTGTTCTAGCCTTGCAAGACATTAACCAACTTAGTGAAGTGAGAAACGCTCAAAGCTTTATTAAAAATATGGGGCA
ATTAATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTTAGCTCTTTGGGTAATTACTTACAAATCTTTAGCTCCAATTCTAGCATGGTAGAACATATTGAAAATCT
TATTAAGCATTACCCTACTACTTGGAAAGAAGTCTTTGTCAATAACACCTATCAAAAATTTGATGACAAAAACACTTAG

Domains

Predicted by InterProScan.

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	46.968	98.709	0.464