Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QDX07_RS09745 Genome accession   NZ_CP122938
Coordinates   2020553..2021209 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain ETEC1701     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2015553..2026209
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QDX07_RS09715 (QDX07_09715) dcyD 2016434..2017420 (+) 987 WP_063086320.1 D-cysteine desulfhydrase -
  QDX07_RS09720 (QDX07_09720) tcyL 2017435..2018103 (+) 669 WP_063086323.1 cystine ABC transporter permease -
  QDX07_RS09725 (QDX07_09725) tcyN 2018100..2018852 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QDX07_RS09730 (QDX07_09730) sdiA 2019081..2019803 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  QDX07_RS09735 (QDX07_09735) yecF 2019870..2020094 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QDX07_RS09740 (QDX07_09740) yecU 2020081..2020257 (-) 177 WP_000590347.1 protein YecU -
  QDX07_RS09745 (QDX07_09745) letA 2020553..2021209 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QDX07_RS09750 (QDX07_09750) uvrC 2021206..2023038 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QDX07_RS09755 (QDX07_09755) pgsA 2023095..2023643 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QDX07_RS09775 (QDX07_09775) yecA 2024293..2024958 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=744094 QDX07_RS09745 WP_000611328.1 2020553..2021209(+) (letA) [Escherichia coli strain ETEC1701]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=744094 QDX07_RS09745 WP_000611328.1 2020553..2021209(+) (letA) [Escherichia coli strain ETEC1701]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACTTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482