Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QDX14_RS09450 Genome accession   NZ_CP122923
Coordinates   1951977..1952633 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain ETEC1703     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1946977..1957633
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QDX14_RS09420 (QDX14_09420) dcyD 1947857..1948843 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  QDX14_RS09425 (QDX14_09425) tcyL 1948858..1949526 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QDX14_RS09430 (QDX14_09430) tcyN 1949523..1950275 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QDX14_RS09435 (QDX14_09435) sdiA 1950505..1951227 (+) 723 WP_224727654.1 transcriptional regulator SdiA -
  QDX14_RS09440 (QDX14_09440) yecF 1951295..1951519 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QDX14_RS09445 (QDX14_09445) yecU 1951506..1951681 (-) 176 Protein_1844 protein YecU -
  QDX14_RS27640 - 1951719..1951835 (-) 117 WP_001302039.1 hypothetical protein -
  QDX14_RS09450 (QDX14_09450) letA 1951977..1952633 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QDX14_RS09455 (QDX14_09455) uvrC 1952630..1954462 (+) 1833 WP_032187456.1 excinuclease ABC subunit UvrC Machinery gene
  QDX14_RS09460 (QDX14_09460) pgsA 1954519..1955067 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QDX14_RS09480 (QDX14_09480) - 1955763..1956089 (-) 327 Protein_1849 hypothetical protein -
  QDX14_RS09485 (QDX14_09485) istA 1956170..1957192 (+) 1023 WP_160371803.1 IS21-like element IS100 family transposase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=743936 QDX14_RS09450 WP_000611335.1 1951977..1952633(+) (letA) [Escherichia coli strain ETEC1703]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=743936 QDX14_RS09450 WP_000611335.1 1951977..1952633(+) (letA) [Escherichia coli strain ETEC1703]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486