Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QDX04_RS09730 Genome accession   NZ_CP122868
Coordinates   1997741..1998397 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain ETEC1721     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1992741..2003397
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QDX04_RS09700 (QDX04_09700) dcyD 1993621..1994607 (+) 987 WP_001128219.1 D-cysteine desulfhydrase -
  QDX04_RS09705 (QDX04_09705) tcyL 1994622..1995290 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QDX04_RS09710 (QDX04_09710) tcyN 1995287..1996039 (+) 753 WP_001272986.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QDX04_RS09715 (QDX04_09715) sdiA 1996269..1996991 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  QDX04_RS09720 (QDX04_09720) yecF 1997058..1997282 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QDX04_RS09725 (QDX04_09725) yecU 1997269..1997445 (-) 177 WP_000590347.1 protein YecU -
  QDX04_RS24200 - 1997528..1997599 (-) 72 Protein_1904 transcriptional regulator -
  QDX04_RS09730 (QDX04_09730) letA 1997741..1998397 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QDX04_RS09735 (QDX04_09735) uvrC 1998394..2000226 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QDX04_RS09740 (QDX04_09740) pgsA 2000283..2000831 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QDX04_RS09760 (QDX04_09760) yecA 2001481..2002146 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=743513 QDX04_RS09730 WP_000611335.1 1997741..1998397(+) (letA) [Escherichia coli strain ETEC1721]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=743513 QDX04_RS09730 WP_000611335.1 1997741..1998397(+) (letA) [Escherichia coli strain ETEC1721]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486