Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QDW95_RS09395 Genome accession   NZ_CP122758
Coordinates   1925190..1925846 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain ETEC1739     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1920190..1930846
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QDW95_RS09365 (QDW95_09365) dcyD 1921070..1922056 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  QDW95_RS09370 (QDW95_09370) tcyL 1922071..1922739 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QDW95_RS09375 (QDW95_09375) tcyN 1922736..1923488 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QDW95_RS09380 (QDW95_09380) sdiA 1923718..1924440 (+) 723 WP_001152713.1 transcriptional regulator SdiA -
  QDW95_RS09385 (QDW95_09385) yecF 1924507..1924731 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QDW95_RS09390 (QDW95_09390) yecU 1924718..1924894 (-) 177 WP_000590347.1 protein YecU -
  QDW95_RS25995 - 1924977..1925048 (-) 72 Protein_1834 transcriptional regulator -
  QDW95_RS09395 (QDW95_09395) letA 1925190..1925846 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QDW95_RS09400 (QDW95_09400) uvrC 1925843..1927675 (+) 1833 WP_001283412.1 excinuclease ABC subunit UvrC Machinery gene
  QDW95_RS09405 (QDW95_09405) pgsA 1927732..1928280 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QDW95_RS09425 (QDW95_09425) - 1928974..1929714 (-) 741 WP_106661694.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=742843 QDW95_RS09395 WP_000611335.1 1925190..1925846(+) (letA) [Escherichia coli strain ETEC1739]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=742843 QDW95_RS09395 WP_000611335.1 1925190..1925846(+) (letA) [Escherichia coli strain ETEC1739]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486