Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   BsBEST3145_RS17660 Genome accession   NZ_AP024625
Coordinates   3360529..3361164 (-) Length   211 a.a.
NCBI ID   WP_003243201.1    Uniprot ID   O32197
Organism   Bacillus subtilis strain BEST3109     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3355529..3366164
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BsBEST3145_RS17640 (BsBEST3109_33890) yvzF 3356585..3356770 (-) 186 WP_003244599.1 YvzF family protein -
  BsBEST3145_RS17645 (BsBEST3109_33900) gerAA 3356888..3358336 (+) 1449 WP_009969097.1 spore germination receptor protein GerAA -
  BsBEST3145_RS17650 (BsBEST3109_33910) gerAB 3358305..3359402 (+) 1098 WP_009968145.1 spore germination receptor protein GerAB -
  BsBEST3145_RS17655 gerAC 3359399..3360521 (+) 1123 Protein_3434 spore germination receptor protein GerAC -
  BsBEST3145_RS17660 (BsBEST3109_33940) vraR 3360529..3361164 (-) 636 WP_003243201.1 two-component system response regulator LiaR Regulator
  BsBEST3145_RS17665 (BsBEST3109_33950) liaS 3361142..3362224 (-) 1083 WP_003244464.1 two-component system sensor histidine kinase LiaS -
  BsBEST3145_RS17670 (BsBEST3109_33960) liaF 3362221..3362946 (-) 726 WP_003242605.1 LiaRS two-component regulatory system accessory protein LiaF -
  BsBEST3145_RS17675 (BsBEST3109_33970) liaG 3362980..3363852 (-) 873 WP_003244420.1 DUF4097 domain-containing protein -
  BsBEST3145_RS17680 (BsBEST3109_33980) liaH 3363953..3364630 (-) 678 WP_003243047.1 stress responsive protein LiaH -
  BsBEST3145_RS17685 (BsBEST3109_33990) liaI 3364657..3365037 (-) 381 WP_003243447.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23124.76 Da        Isoelectric Point: 4.9049

>NTDB_id=74240 BsBEST3145_RS17660 WP_003243201.1 3360529..3361164(-) (vraR) [Bacillus subtilis strain BEST3109]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAVELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=74240 BsBEST3145_RS17660 WP_003243201.1 3360529..3361164(-) (vraR) [Bacillus subtilis strain BEST3109]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGTGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTTACAAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACGAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O32197

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.565

100

0.408